hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06722
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SIRT1 | NAD-dependent protein deacetylase sirtuin-1 (hSIRT1) (EC 3.5.1.-) (Regulatory protein SIR2 homolog 1) (SIR2-like protein 1) (hSIR2) [Cleaved into: SirtT1 75 kDa fragment (75SirT1)] | UniProt NCBI |
| ZBTB38 | Zinc finger and BTB domain-containing protein 38 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:2592 | 0.0249595281251 | 0.5 | SIRT1 | SIRT1 homotrimer complex |
| WP:WP4186 | 0.0332875339197 | 0.5 | SIRT1 | Somatroph axis (GH) and its relationship to dietary restriction and aging |
| WP:WP4191 | 0.0332875339197 | 0.5 | SIRT1 | Caloric restriction and aging |
| CORUM:2593 | 0.0499173803268 | 0.5 | SIRT1 | FOXO3-SIRT1 complex, oxidative stress stimulated |
| CORUM:2821 | 0.0499173803268 | 0.5 | SIRT1 | hSIR2-p53 complex |
| CORUM:6846 | 0.0499173803268 | 0.5 | SIRT1 | DBC1-SIRT1 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SIRT1 | ZBTB38 | 0.738 | 0.738 | bioplex (ZBTB38) bioplex_WMM |
Images
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Complex HuMAP2_06722 has an average edge precision of 0.738 which is ranked 1213 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SIRT1 | HuMAP2_04194 HuMAP2_06722 |
| ZBTB38 | HuMAP2_04194 HuMAP2_06722 |