hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06729
Confidence: Medium High
ProteinsGenename | Protein Name | Links |
---|---|---|
RTF2 | Replication termination factor 2 (RTF2) (Replication termination factor 2 domain-containing protein 1) | UniProt NCBI |
BBOX1 | Gamma-butyrobetaine dioxygenase (EC 1.14.11.1) (Gamma-butyrobetaine hydroxylase) (Gamma-BBH) (Gamma-butyrobetaine,2-oxoglutarate dioxygenase) | UniProt NCBI |
AZI2 | 5-azacytidine-induced protein 2 (NF-kappa-B-activating kinase-associated protein 1) (Nak-associated protein 1) (TILP) | UniProt NCBI |
MTPAP | Poly(A) RNA polymerase, mitochondrial (PAP) (EC 2.7.7.19) (PAP-associated domain-containing protein 1) (Polynucleotide adenylyltransferase) (Terminal uridylyltransferase 1) (TUTase 1) (mtPAP) | UniProt NCBI |
TBK1 | Serine/threonine-protein kinase TBK1 (EC 2.7.11.1) (NF-kappa-B-activating kinase) (T2K) (TANK-binding kinase 1) | UniProt NCBI |
CALCOCO2 | Calcium-binding and coiled-coil domain-containing protein 2 (Antigen nuclear dot 52 kDa protein) (Nuclear domain 10 protein NDP52) (Nuclear domain 10 protein 52) (Nuclear dot protein 52) | UniProt NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
CORUM:5212 | 0.000234668084372 | 0.333333333333 | TBK1 AZI2 | Kinase maturation complex 2 |
WP:WP3865 | 0.00792327646772 | 0.333333333333 | TBK1 AZI2 | Novel intracellular components of RIG-I-like receptor (RLR) pathway |
KEGG:04137 | 0.0117137285677 | 0.333333333333 | TBK1 CALCOCO2 | Mitophagy - animal |
KEGG:04622 | 0.0124835568261 | 0.333333333333 | TBK1 AZI2 | RIG-I-like receptor signaling pathway |
CORUM:7405 | 0.0499726005494 | 0.166666666667 | TBK1 | TMEM173-TBK1 complex |
Edges
Protein 1 | Protein 2 | Score | Precision | Evidence |
---|---|---|---|---|
BBOX1 | RTF2 | 0.622 | 0.677 | bioplex (BBOX1) bioplex_WMM |
BBOX1 | AZI2 | 0.598 | 0.668 | bioplex (BBOX1) bioplex_WMM |
CALCOCO2 | AZI2 | 0.553 | 0.646 | bioplex (CALCOCO2) bioplex_WMM |
BBOX1 | TBK1 | 0.453 | 0.594 | bioplex (BBOX1) bioplex_WMM |
CALCOCO2 | MTPAP | 0.093 | 0.355 | bioplex (CALCOCO2) bioplex_WMM |
CALCOCO2 | TBK1 | 0.046 | 0.293 | bioplex (CALCOCO2) bioplex_WMM |
AZI2 | TBK1 | 0.014 | 0.138 | youn (TBK1) bioplex_WMM youn_WMM |
RTF2 | AZI2 | 0.009 | 0.096 | bioplex_WMM WMM_only |
MTPAP | AZI2 | 0.007 | 0.006 | bioplex_WMM WMM_only |
CALCOCO2 | RTF2 | 0.007 | 0.006 | bioplex_WMM WMM_only |
MTPAP | RTF2 | 0.007 | 0.003 | youn_WMM WMM_only |
MTPAP | TBK1 | 0.007 | 0.001 | bioplex_WMM youn_WMM WMM_only |
RTF2 | TBK1 | 0.0 | 0.01 | bioplex_WMM fraction |
CALCOCO2 | BBOX1 | 0.0 | 0.003 | bioplex (BBOX1) bioplex_WMM |
Images
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Complex HuMAP2_06729 has an average edge precision of 0.25 which is ranked 5380 out of all 6965 complexes.
Related Complexes