hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06735
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PABPC1 | Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1) | UniProt NCBI |
| PAIP2 | Polyadenylate-binding protein-interacting protein 2 (PABP-interacting protein 2) (PAIP-2) (Poly(A)-binding protein-interacting protein 2) | UniProt NCBI |
| ANKRD17 | Ankyrin repeat domain-containing protein 17 (Gene trap ankyrin repeat protein) (Serologically defined breast cancer antigen NY-BR-16) | UniProt NCBI |
| LARP4 | La-related protein 4 (La ribonucleoprotein domain family member 4) | UniProt NCBI |
| ZCCHC3 | Zinc finger CCHC domain-containing protein 3 | UniProt NCBI |
| PAIP1 | Polyadenylate-binding protein-interacting protein 1 (PABP-interacting protein 1) (PAIP-1) (Poly(A)-binding protein-interacting protein 1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1307 | 8.38550741504e-05 | 0.333333333333 | PABPC1 PAIP1 | Multiprotein complex (mRNA turnover) |
| REAC:R-HSA-429947 | 0.00662414399653 | 0.333333333333 | PABPC1 PAIP1 | Deadenylation of mRNA |
| WP:WP107 | 0.0067875461385 | 0.333333333333 | PABPC1 PAIP1 | Translation Factors |
| REAC:R-HSA-429914 | 0.0338154872995 | 0.333333333333 | PABPC1 PAIP1 | Deadenylation-dependent mRNA decay |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PAIP1 | PABPC1 | 0.979 | 0.895 | hein_WMM youn (PABPC1,PAIP1) bioplex_WMM youn_WMM hein (PABPC1) gupta_WMM fraction |
| PABPC1 | LARP4 | 0.448 | 0.592 | hein_WMM youn (PABPC1) bioplex (LARP4) bioplex_WMM youn_WMM hein (PABPC1) gupta_WMM fraction treiber_WMM |
| PABPC1 | ANKRD17 | 0.365 | 0.544 | hein_WMM youn (ANKRD17,PABPC1) bioplex_WMM youn_WMM gupta_WMM fraction |
| PAIP1 | ZCCHC3 | 0.318 | 0.51 | youn (PAIP1) bioplex (PAIP1) bioplex_WMM youn_WMM |
| PAIP1 | PAIP2 | 0.047 | 0.294 | youn (PAIP1,PAIP2) bioplex (PAIP1) bioplex_WMM youn_WMM |
| PAIP2 | PABPC1 | 0.047 | 0.291 | youn (PABPC1,PAIP2) bioplex_WMM youn_WMM |
| PAIP2 | ZCCHC3 | 0.008 | 0.033 | youn (PAIP2) bioplex_WMM youn_WMM |
| PAIP2 | ANKRD17 | 0.007 | 0.01 | youn (ANKRD17,PAIP2) bioplex_WMM youn_WMM |
| PAIP1 | ANKRD17 | 0.007 | 0.009 | youn (PAIP1) bioplex_WMM youn_WMM gupta_WMM |
| ZCCHC3 | LARP4 | 0.007 | 0.004 | bioplex_WMM youn_WMM WMM_only |
| ZCCHC3 | ANKRD17 | 0.007 | 0.008 | bioplex_WMM youn_WMM WMM_only |
| ANKRD17 | LARP4 | 0.005 | 0.008 | hein_WMM youn (ANKRD17) bioplex_WMM youn_WMM gupta_WMM |
| PAIP2 | LARP4 | 0.004 | 0.013 | youn (PAIP2) bioplex_WMM youn_WMM |
| PAIP1 | LARP4 | 0.004 | 0.011 | hein_WMM youn (PAIP1) bioplex_WMM youn_WMM |
| ZCCHC3 | PABPC1 | 0.004 | 0.006 | youn (PABPC1) bioplex_WMM youn_WMM treiber_WMM |
Images
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Complex HuMAP2_06735 has an average edge precision of 0.215 which is ranked 5941 out of all 6965 complexes.
Related Complexes