hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06737
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| MAD2L1BP | MAD2L1-binding protein (Caught by MAD2 protein) (p31(comet)) | UniProt NCBI |
| EMD | Emerin | UniProt NCBI |
| MAD2L1 | Mitotic spindle assembly checkpoint protein MAD2A (HsMAD2) (Mitotic arrest deficient 2-like protein 1) (MAD2-like protein 1) | UniProt NCBI |
| NTF3 | Neurotrophin-3 (NT-3) (HDNF) (Nerve growth factor 2) (NGF-2) (Neurotrophic factor) | UniProt NCBI |
| CAMK1 | Calcium/calmodulin-dependent protein kinase type 1 (EC 2.7.11.17) (CaM kinase I) (CaM-KI) (CaM kinase I alpha) (CaMKI-alpha) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:5408 | 0.0249780992026 | 0.2 | NTF3 | Neurotrophin-3-p75 complex |
| WP:WP2380 | 0.0301079862712 | 0.4 | CAMK1 NTF3 | Brain-Derived Neurotrophic Factor (BDNF) signaling pathway |
| CORUM:1814 | 0.0499494897235 | 0.2 | MAD2L1 | MAD1L1-MAD2L1 complex |
| CORUM:2718 | 0.0499494897235 | 0.2 | MAD2L1 | MAD2-CDC20 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| MAD2L1 | MAD2L1BP | 0.066 | 0.349 | hein_WMM bioplex_WMM hein (MAD2L1,MAD2L1BP) |
| MAD2L1BP | NTF3 | 0.029 | 0.23 | bioplex (NTF3) bioplex_WMM |
| EMD | MAD2L1 | 0.028 | 0.233 | hein_WMM bioplex_WMM boldt youn_WMM hein (MAD2L1) gupta_WMM boldt_WMM |
| MAD2L1BP | CAMK1 | 0.022 | 0.206 | hein_WMM hein (MAD2L1BP) |
| MAD2L1 | CAMK1 | 0.007 | 0.007 | hein_WMM bioplex_WMM WMM_only |
| EMD | MAD2L1BP | 0.007 | 0.006 | hein_WMM WMM_only |
| EMD | CAMK1 | 0.007 | 0.0 | bioplex_WMM WMM_only |
| EMD | NTF3 | 0.007 | 0.005 | bioplex (NTF3) |
| MAD2L1 | NTF3 | 0.0 | 0.012 | bioplex (NTF3) bioplex_WMM |
Images
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Complex HuMAP2_06737 has an average edge precision of 0.116 which is ranked 6887 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| MAD2L1BP | HuMAP2_01926 HuMAP2_04132 HuMAP2_06737 |
| EMD | HuMAP2_00382 HuMAP2_06737 |
| MAD2L1 | HuMAP2_01926 HuMAP2_06737 |
| NTF3 | HuMAP2_04132 HuMAP2_06737 |
| CAMK1 | HuMAP2_04132 HuMAP2_05830 HuMAP2_06431 HuMAP2_06737 |