hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06742
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| FBP1 | Fructose-1,6-bisphosphatase 1 (FBPase 1) (EC 3.1.3.11) (D-fructose-1,6-bisphosphate 1-phosphohydrolase 1) (Liver FBPase) | UniProt NCBI |
| GLRX5 | Glutaredoxin-related protein 5, mitochondrial (Monothiol glutaredoxin-5) | UniProt NCBI |
| FBP2 | Fructose-1,6-bisphosphatase isozyme 2 (FBPase 2) (EC 3.1.3.11) (D-fructose-1,6-bisphosphate 1-phosphohydrolase 2) (Muscle FBPase) | UniProt NCBI |
| AARS | Alanine--tRNA ligase, cytoplasmic (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS) (Renal carcinoma antigen NY-REN-42) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00030 | 0.000811520562786 | 0.5 | FBP2 FBP1 | Pentose phosphate pathway |
| KEGG:00051 | 0.00105499815766 | 0.5 | FBP2 FBP1 | Fructose and mannose metabolism |
| WP:WP534 | 0.0015833920549 | 0.5 | FBP2 FBP1 | Glycolysis and Gluconeogenesis |
| GO:0042132 | 0.00270494046827 | 0.5 | FBP2 FBP1 | fructose 1,6-bisphosphate 1-phosphatase activity |
| GO:0005986 | 0.00270494046827 | 0.5 | FBP2 FBP1 | sucrose biosynthetic process |
| KEGG:00010 | 0.00389180767222 | 0.5 | FBP2 FBP1 | Glycolysis / Gluconeogenesis |
| REAC:R-HSA-70263 | 0.00436320194063 | 0.5 | FBP2 FBP1 | Gluconeogenesis |
| GO:0005985 | 0.00811409485621 | 0.5 | FBP2 FBP1 | sucrose metabolic process |
| KEGG:04922 | 0.00905997214328 | 0.5 | FBP2 FBP1 | Glucagon signaling pathway |
| KEGG:04152 | 0.0123324218825 | 0.5 | FBP2 FBP1 | AMPK signaling pathway |
| KEGG:01200 | 0.012776519361 | 0.5 | FBP2 FBP1 | Carbon metabolism |
| KEGG:04910 | 0.0153578793248 | 0.5 | FBP2 FBP1 | Insulin signaling pathway |
| GO:0046351 | 0.0270421395626 | 0.5 | FBP2 FBP1 | disaccharide biosynthetic process |
| REAC:R-HSA-70326 | 0.0331557329305 | 0.5 | FBP2 FBP1 | Glucose metabolism |
| HP:0002904 | 0.0348360947433 | 0.5 | GLRX5 FBP1 | Hyperbilirubinemia |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| FBP1 | FBP2 | 0.999 | 0.946 | bioplex (FBP1,FBP2) bioplex_WMM |
| FBP1 | AARS | 0.18 | 0.437 | bioplex_WMM fraction |
| FBP1 | GLRX5 | 0.109 | 0.375 | fraction |
| AARS | GLRX5 | 0.0 | 0.0 | bioplex_WMM fraction |
Images
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Complex HuMAP2_06742 has an average edge precision of 0.44 which is ranked 2940 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| FBP1 | HuMAP2_01959 HuMAP2_04844 HuMAP2_05148 HuMAP2_06742 |
| GLRX5 | HuMAP2_06583 HuMAP2_06742 |
| FBP2 | HuMAP2_01959 HuMAP2_04844 HuMAP2_05148 HuMAP2_06742 |
| AARS | HuMAP2_02706 HuMAP2_06742 HuMAP2_06869 |