hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06749
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| EXOC1 | Exocyst complex component 1 (Exocyst complex component Sec3) | UniProt NCBI |
| EXOC4 | Exocyst complex component 4 (Exocyst complex component Sec8) | UniProt NCBI |
| EXOC2 | Exocyst complex component 2 (Exocyst complex component Sec5) | UniProt NCBI |
| EXOC3 | Exocyst complex component 3 (Exocyst complex component Sec6) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:89 | 3.17414367033e-12 | 1.0 | EXOC1 EXOC3 EXOC4 EXOC2 | Exocyst Sec6/8 complex |
| CORUM:6167 | 3.17414367033e-12 | 1.0 | EXOC1 EXOC3 EXOC4 EXOC2 | Exocyst complex |
| REAC:R-HSA-5620916 | 3.51513739035e-10 | 1.0 | EXOC1 EXOC3 EXOC4 EXOC2 | VxPx cargo-targeting to cilium |
| REAC:R-HSA-264876 | 9.63670018313e-10 | 1.0 | EXOC1 EXOC3 EXOC4 EXOC2 | Insulin processing |
| REAC:R-HSA-5620920 | 1.61758895931e-08 | 1.0 | EXOC1 EXOC3 EXOC4 EXOC2 | Cargo trafficking to the periciliary membrane |
| GO:0000145 | 1.74428263667e-08 | 1.0 | EXOC1 EXOC3 EXOC4 EXOC2 | exocyst |
| REAC:R-HSA-1445148 | 7.38564283704e-08 | 1.0 | EXOC1 EXOC3 EXOC4 EXOC2 | Translocation of SLC2A4 (GLUT4) to the plasma membrane |
| REAC:R-HSA-2980736 | 7.84014393471e-08 | 1.0 | EXOC1 EXOC3 EXOC4 EXOC2 | Peptide hormone metabolism |
| WP:WP4352 | 1.2395315779e-06 | 1.0 | EXOC1 EXOC3 EXOC4 EXOC2 | Ciliary landscape |
| REAC:R-HSA-5617833 | 4.87252320159e-06 | 1.0 | EXOC1 EXOC3 EXOC4 EXOC2 | Cilium Assembly |
| GO:0099023 | 8.96024572897e-06 | 1.0 | EXOC1 EXOC3 EXOC4 EXOC2 | vesicle tethering complex |
| REAC:R-HSA-1852241 | 2.24070737955e-05 | 1.0 | EXOC1 EXOC3 EXOC4 EXOC2 | Organelle biogenesis and maintenance |
| GO:0044448 | 0.000342608092204 | 1.0 | EXOC1 EXOC3 EXOC4 EXOC2 | cell cortex part |
| REAC:R-HSA-199991 | 0.000426145417081 | 1.0 | EXOC1 EXOC3 EXOC4 EXOC2 | Membrane Trafficking |
| REAC:R-HSA-5653656 | 0.000528360370521 | 1.0 | EXOC1 EXOC3 EXOC4 EXOC2 | Vesicle-mediated transport |
| GO:0005938 | 0.00151538042626 | 1.0 | EXOC1 EXOC3 EXOC4 EXOC2 | cell cortex |
| GO:0006893 | 0.00710332146687 | 0.75 | EXOC1 EXOC4 EXOC2 | Golgi to plasma membrane transport |
| GO:0099568 | 0.00785572034373 | 1.0 | EXOC1 EXOC3 EXOC4 EXOC2 | cytoplasmic region |
| GO:0098876 | 0.0244411426287 | 0.75 | EXOC1 EXOC4 EXOC2 | vesicle-mediated transport to the plasma membrane |
| GO:0051601 | 0.0270421395626 | 0.5 | EXOC1 EXOC3 | exocyst localization |
| REAC:R-HSA-392499 | 0.0403329683602 | 1.0 | EXOC1 EXOC3 EXOC4 EXOC2 | Metabolism of proteins |
| GO:0006892 | 0.0469269676219 | 0.75 | EXOC1 EXOC4 EXOC2 | post-Golgi vesicle-mediated transport |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| EXOC1 | EXOC2 | 1.0 | 0.949 | bioplex (EXOC1) bioplex_WMM boldt (EXOC1,EXOC2) Malo fraction boldt_WMM |
| EXOC4 | EXOC2 | 1.0 | 0.949 | bioplex_WMM boldt (EXOC2,EXOC4) youn_WMM Malo fraction boldt_WMM treiber_WMM |
| EXOC1 | EXOC4 | 0.999 | 0.949 | bioplex (EXOC1) bioplex_WMM boldt (EXOC1,EXOC4) Malo fraction boldt_WMM |
| EXOC4 | EXOC3 | 0.998 | 0.943 | bioplex (EXOC3) bioplex_WMM boldt (EXOC3,EXOC4) Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| EXOC2 | EXOC3 | 0.99 | 0.909 | bioplex (EXOC3) bioplex_WMM boldt (EXOC2,EXOC3) Malo fraction boldt_WMM treiber_WMM |
| EXOC1 | EXOC3 | 0.988 | 0.902 | bioplex (EXOC1,EXOC3) bioplex_WMM boldt (EXOC1,EXOC3) Malo fraction boldt_WMM |
Images
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Complex HuMAP2_06749 has an average edge precision of 0.933 which is ranked 423 out of all 6965 complexes.
Related Complexes