hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_06764
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| DYNLRB2 | Dynein light chain roadblock-type 2 (Dynein light chain 2B, cytoplasmic) (Roadblock domain-containing protein 2) | UniProt NCBI |
| ENO1 | Alpha-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (C-myc promoter-binding protein) (Enolase 1) (MBP-1) (MPB-1) (Non-neural enolase) (NNE) (Phosphopyruvate hydratase) (Plasminogen-binding protein) | UniProt NCBI |
| FKBP7 | Peptidyl-prolyl cis-trans isomerase FKBP7 (PPIase FKBP7) (EC 5.2.1.8) (23 kDa FK506-binding protein) (23 kDa FKBP) (FKBP-23) (FK506-binding protein 7) (FKBP-7) (Rotamase) | UniProt NCBI |
| ALDOC | Fructose-bisphosphate aldolase C (EC 4.1.2.13) (Brain-type aldolase) | UniProt NCBI |
| IRS1 | Insulin receptor substrate 1 (IRS-1) | UniProt NCBI |
| SPR | Sepiapterin reductase (SPR) (EC 1.1.1.153) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP534 | 0.00524729006009 | 0.333333333333 | ALDOC ENO1 | Glycolysis and Gluconeogenesis |
| REAC:R-HSA-70263 | 0.00959640616298 | 0.333333333333 | ALDOC ENO1 | Gluconeogenesis |
| KEGG:00010 | 0.0120956152943 | 0.333333333333 | ALDOC ENO1 | Glycolysis / Gluconeogenesis |
| KEGG:01230 | 0.0153684049392 | 0.333333333333 | ALDOC ENO1 | Biosynthesis of amino acids |
| WP:WP4018 | 0.0174151198914 | 0.333333333333 | ALDOC ENO1 | Pathways in clear cell renal cell carcinoma |
| KEGG:04066 | 0.0304541793376 | 0.333333333333 | ALDOC ENO1 | HIF-1 signaling pathway |
| KEGG:01200 | 0.039527830217 | 0.333333333333 | ALDOC ENO1 | Carbon metabolism |
| REAC:R-HSA-70171 | 0.0470157324282 | 0.333333333333 | ALDOC ENO1 | Glycolysis |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ENO1 | ALDOC | 0.447 | 0.59 | bioplex (ALDOC) bioplex_WMM Guru fraction treiber_WMM |
| FKBP7 | IRS1 | 0.371 | 0.546 | bioplex (FKBP7) bioplex_WMM |
| FKBP7 | ENO1 | 0.285 | 0.49 | bioplex (FKBP7) bioplex_WMM Guru fraction |
| FKBP7 | ALDOC | 0.075 | 0.356 | bioplex_WMM Guru fraction |
| SPR | ENO1 | 0.071 | 0.352 | fraction treiber_WMM |
| DYNLRB2 | ENO1 | 0.041 | 0.268 | fraction |
| ENO1 | IRS1 | 0.007 | 0.002 | WMM_only boldt_WMM |
| SPR | ALDOC | 0.0 | 0.0 | bioplex_WMM fraction treiber_WMM |
Images
Click to enlarge
Complex HuMAP2_06764 has an average edge precision of 0.325 which is ranked 4272 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| DYNLRB2 | HuMAP2_01126 HuMAP2_06660 HuMAP2_06764 |
| ENO1 | HuMAP2_01126 HuMAP2_01883 HuMAP2_05130 HuMAP2_05943 HuMAP2_06764 HuMAP2_06767 |
| FKBP7 | HuMAP2_01126 HuMAP2_02739 HuMAP2_06764 |
| ALDOC | HuMAP2_01418 HuMAP2_03109 HuMAP2_04230 HuMAP2_04680 HuMAP2_06764 |
| IRS1 | HuMAP2_02739 HuMAP2_06764 |
| SPR | HuMAP2_00122 HuMAP2_00572 HuMAP2_01126 HuMAP2_01232 HuMAP2_05577 HuMAP2_05985 HuMAP2_06764 |