hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06766
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NOB1 | RNA-binding protein NOB1 (Phosphorylation regulatory protein HP-10) (Protein ART-4) | UniProt NCBI |
| UTP14C | U3 small nucleolar RNA-associated protein 14 homolog C | UniProt NCBI |
| FEN1 | Flap endonuclease 1 (FEN-1) (EC 3.1.-.-) (DNase IV) (Flap structure-specific endonuclease 1) (Maturation factor 1) (MF1) (hFEN-1) | UniProt NCBI |
| PNO1 | RNA-binding protein PNO1 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-6791226 | 0.00130084091532 | 0.75 | NOB1 UTP14C PNO1 | Major pathway of rRNA processing in the nucleolus and cytosol |
| REAC:R-HSA-8868773 | 0.00152914291965 | 0.75 | NOB1 UTP14C PNO1 | rRNA processing in the nucleus and cytosol |
| REAC:R-HSA-72312 | 0.00178261497865 | 0.75 | NOB1 UTP14C PNO1 | rRNA processing |
| KEGG:03008 | 0.00582341320088 | 0.5 | NOB1 UTP14C | Ribosome biogenesis in eukaryotes |
| REAC:R-HSA-6790901 | 0.0177060142151 | 0.5 | UTP14C PNO1 | rRNA modification in the nucleus and cytosol |
| CORUM:7282 | 0.0499140284799 | 0.25 | FEN1 | FEN1-WRN complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| UTP14C | PNO1 | 0.296 | 0.496 | bioplex (PNO1) bioplex_WMM youn_WMM |
| NOB1 | PNO1 | 0.059 | 0.328 | hein_WMM bioplex (NOB1,PNO1) bioplex_WMM youn_WMM gupta_WMM fraction |
| FEN1 | PNO1 | 0.023 | 0.211 | youn_WMM gupta_WMM fraction treiber_WMM |
| NOB1 | UTP14C | 0.008 | 0.089 | bioplex_WMM WMM_only |
| FEN1 | UTP14C | 0.007 | 0.005 | youn_WMM WMM_only |
| FEN1 | NOB1 | 0.007 | 0.002 | youn_WMM gupta_WMM WMM_only |
Images
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Complex HuMAP2_06766 has an average edge precision of 0.189 which is ranked 6326 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| NOB1 | HuMAP2_02559 HuMAP2_03347 HuMAP2_03680 HuMAP2_05710 HuMAP2_06629 HuMAP2_06766 |
| UTP14C | HuMAP2_02559 HuMAP2_03347 HuMAP2_06766 |
| FEN1 | HuMAP2_00386 HuMAP2_01543 HuMAP2_05422 HuMAP2_06224 HuMAP2_06766 |
| PNO1 | HuMAP2_02559 HuMAP2_03347 HuMAP2_05710 HuMAP2_06766 |