hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06768
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| POFUT2 | GDP-fucose protein O-fucosyltransferase 2 (EC 2.4.1.221) (Peptide-O-fucosyltransferase 2) (O-FucT-2) | UniProt NCBI |
| OTUB1 | Ubiquitin thioesterase OTUB1 (EC 3.4.19.12) (Deubiquitinating enzyme OTUB1) (OTU domain-containing ubiquitin aldehyde-binding protein 1) (Otubain-1) (hOTU1) (Ubiquitin-specific-processing protease OTUB1) | UniProt NCBI |
| OTUD6B | Deubiquitinase OTUD6B (EC 3.4.19.12) (DUBA-5) (OTU domain-containing protein 6B) | UniProt NCBI |
| HSPA14 | Heat shock 70 kDa protein 14 (HSP70-like protein 1) (Heat shock protein HSP60) | UniProt NCBI |
| DENR | Density-regulated protein (DRP) (Protein DRP1) (Smooth muscle cell-associated protein 3) (SMAP-3) | UniProt NCBI |
| NFAM1 | NFAT activation molecule 1 (Calcineurin/NFAT-activating ITAM-containing protein) (NFAT-activating protein with ITAM motif 1) | UniProt NCBI |
| FKBP3 | Peptidyl-prolyl cis-trans isomerase FKBP3 (PPIase FKBP3) (EC 5.2.1.8) (25 kDa FK506-binding protein) (25 kDa FKBP) (FKBP-25) (FK506-binding protein 3) (FKBP-3) (Immunophilin FKBP25) (Rapamycin-selective 25 kDa immunophilin) (Rotamase) | UniProt NCBI |
| MCTS1 | Malignant T-cell-amplified sequence 1 (MCT-1) (Multiple copies T-cell malignancies) | UniProt NCBI |
| PRC1 | Protein regulator of cytokinesis 1 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0002188 | 0.0486736709081 | 0.222222222222 | MCTS1 DENR | translation reinitiation |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DENR | MCTS1 | 1.0 | 0.949 | bioplex (DENR) bioplex_WMM gupta_WMM fraction |
| MCTS1 | OTUD6B | 0.998 | 0.944 | fraction |
| DENR | OTUD6B | 0.116 | 0.386 | fraction |
| HSPA14 | MCTS1 | 0.077 | 0.351 | bioplex_WMM fraction |
| HSPA14 | NFAM1 | 0.057 | 0.324 | bioplex (NFAM1) bioplex_WMM |
| OTUD6B | OTUB1 | 0.041 | 0.271 | fraction |
| POFUT2 | MCTS1 | 0.038 | 0.261 | fraction |
| MCTS1 | OTUB1 | 0.03 | 0.24 | bioplex_WMM gupta_WMM fraction treiber_WMM |
| HSPA14 | FKBP3 | 0.026 | 0.22 | gupta_WMM fraction |
| HSPA14 | PRC1 | 0.022 | 0.205 | fraction |
| DENR | PRC1 | 0.021 | 0.189 | fraction |
| DENR | FKBP3 | 0.02 | 0.185 | bioplex_WMM youn_WMM gupta_WMM fraction |
| DENR | POFUT2 | 0.013 | 0.143 | fraction |
| MCTS1 | FKBP3 | 0.012 | 0.149 | bioplex_WMM gupta_WMM fraction treiber_WMM |
| DENR | OTUB1 | 0.011 | 0.141 | bioplex_WMM gupta_WMM fraction |
| OTUB1 | FKBP3 | 0.01 | 0.13 | bioplex_WMM gupta_WMM fraction treiber_WMM |
| HSPA14 | DENR | 0.009 | 0.108 | fraction |
| POFUT2 | FKBP3 | 0.007 | 0.0 | bioplex_WMM WMM_only |
| POFUT2 | OTUB1 | 0.007 | 0.004 | bioplex_WMM WMM_only |
| PRC1 | OTUB1 | 0.007 | 0.001 | boldt youn_WMM boldt_WMM |
| HSPA14 | OTUD6B | 0.004 | 0.014 | fraction |
| PRC1 | FKBP3 | 0.004 | 0.011 | gupta_WMM fraction |
| OTUD6B | FKBP3 | 0.0 | 0.009 | fraction |
| OTUD6B | PRC1 | 0.0 | 0.009 | fraction |
| MCTS1 | PRC1 | 0.0 | 0.0 | fraction |
| HSPA14 | OTUB1 | 0.0 | 0.0 | bioplex_WMM youn_WMM fraction |
Images
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Complex HuMAP2_06768 has an average edge precision of 0.202 which is ranked 6158 out of all 6965 complexes.
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