hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06776
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| UBE2V1 | Ubiquitin-conjugating enzyme E2 variant 1 (UEV-1) (CROC-1) (TRAF6-regulated IKK activator 1 beta Uev1A) | UniProt NCBI |
| FKBP2 | Peptidyl-prolyl cis-trans isomerase FKBP2 (PPIase FKBP2) (EC 5.2.1.8) (13 kDa FK506-binding protein) (13 kDa FKBP) (FKBP-13) (FK506-binding protein 2) (FKBP-2) (Immunophilin FKBP13) (Rotamase) | UniProt NCBI |
| GPX4 | Phospholipid hydroperoxide glutathione peroxidase (PHGPx) (EC 1.11.1.12) (Glutathione peroxidase 4) (GPx-4) (GSHPx-4) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6025 | 0.0499776345577 | 0.333333333333 | UBE2V1 | Ubiquitin-conjugating enzyme E2 (UBC13-UEV1A) |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| FKBP2 | GPX4 | 0.954 | 0.861 | Guru fraction |
| FKBP2 | UBE2V1 | 0.926 | 0.843 | bioplex_WMM Guru fraction |
| GPX4 | UBE2V1 | 0.016 | 0.161 | bioplex (GPX4) bioplex_WMM Guru fraction |
Images
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Complex HuMAP2_06776 has an average edge precision of 0.622 which is ranked 1817 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| UBE2V1 | HuMAP2_04049 HuMAP2_04953 HuMAP2_05643 HuMAP2_05780 HuMAP2_06767 HuMAP2_06776 |
| FKBP2 | HuMAP2_01636 HuMAP2_03277 HuMAP2_05984 HuMAP2_06767 HuMAP2_06776 |
| GPX4 | HuMAP2_02425 HuMAP2_02733 HuMAP2_03443 HuMAP2_06776 |