hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06782
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PKN1 | Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protease-activated kinase 1) (PAK-1) (Protein kinase C-like 1) (Protein kinase C-like PKN) (Protein kinase PKN-alpha) (Protein-kinase C-related kinase 1) (Serine-threonine protein kinase N) | UniProt NCBI |
| KLHL12 | Kelch-like protein 12 (CUL3-interacting protein 1) (DKIR homolog) (hDKIR) | UniProt NCBI |
| DDX3Y | ATP-dependent RNA helicase DDX3Y (EC 3.6.4.13) (DEAD box protein 3, Y-chromosomal) | UniProt NCBI |
| EWSR1 | RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein) | UniProt NCBI |
| NUDCD2 | NudC domain-containing protein 2 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6815 | 0.0499494897235 | 0.2 | KLHL12 | DRD4-KLHL12-CUL3 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DDX3Y | NUDCD2 | 0.709 | 0.728 | bioplex (NUDCD2) bioplex_WMM gupta_WMM |
| DDX3Y | EWSR1 | 0.072 | 0.354 | youn_WMM gupta_WMM fraction |
| KLHL12 | EWSR1 | 0.032 | 0.241 | hein_WMM bioplex_WMM hein (EWSR1) |
| EWSR1 | PKN1 | 0.022 | 0.198 | gupta_WMM fraction |
| EWSR1 | NUDCD2 | 0.007 | 0.001 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| KLHL12 | NUDCD2 | 0.005 | 0.009 | bioplex (NUDCD2) bioplex_WMM |
Images
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Complex HuMAP2_06782 has an average edge precision of 0.255 which is ranked 5298 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PKN1 | HuMAP2_02575 HuMAP2_03618 HuMAP2_06782 |
| KLHL12 | HuMAP2_00696 HuMAP2_02675 HuMAP2_06782 |
| DDX3Y | HuMAP2_00696 HuMAP2_01808 HuMAP2_04410 HuMAP2_04761 HuMAP2_05868 HuMAP2_06185 HuMAP2_06400 HuMAP2_06782 |
| EWSR1 | HuMAP2_00696 HuMAP2_05868 HuMAP2_06782 |
| NUDCD2 | HuMAP2_00696 HuMAP2_01808 HuMAP2_04410 HuMAP2_04761 HuMAP2_05868 HuMAP2_06400 HuMAP2_06782 |