hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06786
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| VPS39 | Vam6/Vps39-like protein (TRAP1-like protein) (hVam6p) | UniProt NCBI |
| ZNF263 | Zinc finger protein 263 (Zinc finger protein FPM315) (Zinc finger protein with KRAB and SCAN domains 12) | UniProt NCBI |
| RPS6KC1 | Ribosomal protein S6 kinase delta-1 (S6K-delta-1) (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase) (Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein) (SPHK1-binding protein) | UniProt NCBI |
| USP54 | Inactive ubiquitin carboxyl-terminal hydrolase 54 (Inactive ubiquitin-specific peptidase 54) | UniProt NCBI |
| CEP89 | Centrosomal protein of 89 kDa (Cep89) (Centrosomal protein 123) (Cep123) (Coiled-coil domain-containing protein 123) | UniProt NCBI |
| DENND6A | Protein DENND6A (DENN domain-containing protein 6A) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6118 | 0.0499726005494 | 0.166666666667 | VPS39 | Hook1-Vps39 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RPS6KC1 | VPS39 | 0.941 | 0.854 | bioplex (VPS39) bioplex_WMM |
| USP54 | VPS39 | 0.032 | 0.245 | bioplex (VPS39) bioplex_WMM |
| CEP89 | ZNF263 | 0.027 | 0.224 | bioplex (ZNF263) bioplex_WMM |
| VPS39 | ZNF263 | 0.026 | 0.22 | bioplex (ZNF263) bioplex_WMM |
| RPS6KC1 | DENND6A | 0.02 | 0.184 | hein_WMM hein (DENND6A) |
| CEP89 | VPS39 | 0.008 | 0.041 | bioplex_WMM WMM_only |
| USP54 | RPS6KC1 | 0.007 | 0.009 | bioplex_WMM WMM_only |
| USP54 | DENND6A | 0.007 | 0.003 | bioplex_WMM youn_WMM WMM_only |
| CEP89 | USP54 | 0.004 | 0.017 | youn_WMM gupta_WMM gupta (CEP89) |
Images
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Complex HuMAP2_06786 has an average edge precision of 0.2 which is ranked 6180 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| VPS39 | HuMAP2_04274 HuMAP2_06786 |
| ZNF263 | HuMAP2_06786 |
| RPS6KC1 | HuMAP2_00810 HuMAP2_04274 HuMAP2_06786 |
| USP54 | HuMAP2_00618 HuMAP2_03772 HuMAP2_06786 |
| CEP89 | HuMAP2_00559 HuMAP2_02644 HuMAP2_03208 HuMAP2_05248 HuMAP2_06534 HuMAP2_06786 |
| DENND6A | HuMAP2_00810 HuMAP2_06786 |