hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06807
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PFKM | ATP-dependent 6-phosphofructokinase, muscle type (ATP-PFK) (PFK-M) (EC 2.7.1.11) (6-phosphofructokinase type A) (Phosphofructo-1-kinase isozyme A) (PFK-A) (Phosphohexokinase) | UniProt NCBI |
| PFKL | ATP-dependent 6-phosphofructokinase, liver type (ATP-PFK) (PFK-L) (EC 2.7.1.11) (6-phosphofructokinase type B) (Phosphofructo-1-kinase isozyme B) (PFK-B) (Phosphohexokinase) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00052 | 5.12100379916e-05 | 1.0 | PFKM PFKL | Galactose metabolism |
| KEGG:00030 | 5.9234402919e-05 | 1.0 | PFKM PFKL | Pentose phosphate pathway |
| KEGG:00051 | 7.70339033036e-05 | 1.0 | PFKM PFKL | Fructose and mannose metabolism |
| KEGG:00010 | 0.000284937903697 | 1.0 | PFKM PFKL | Glycolysis / Gluconeogenesis |
| KEGG:05230 | 0.000322579470084 | 1.0 | PFKM PFKL | Central carbon metabolism in cancer |
| WP:WP534 | 0.000352461939805 | 1.0 | PFKM PFKL | Glycolysis and Gluconeogenesis |
| KEGG:01230 | 0.000362555397177 | 1.0 | PFKM PFKL | Biosynthesis of amino acids |
| KEGG:03018 | 0.000415808000786 | 1.0 | PFKM PFKL | RNA degradation |
| KEGG:04922 | 0.000665292801258 | 1.0 | PFKM PFKL | Glucagon signaling pathway |
| KEGG:04066 | 0.000722192843471 | 1.0 | PFKM PFKL | HIF-1 signaling pathway |
| KEGG:04152 | 0.000906899134346 | 1.0 | PFKM PFKL | AMPK signaling pathway |
| KEGG:01200 | 0.000939726081777 | 1.0 | PFKM PFKL | Carbon metabolism |
| WP:WP4018 | 0.00117735700823 | 1.0 | PFKM PFKL | Pathways in clear cell renal cell carcinoma |
| GO:0003872 | 0.00135247023414 | 1.0 | PFKM PFKL | 6-phosphofructokinase activity |
| GO:0005945 | 0.00135247023414 | 1.0 | PFKM PFKL | 6-phosphofructokinase complex |
| GO:0070095 | 0.00270494046827 | 1.0 | PFKM PFKL | fructose-6-phosphate binding |
| REAC:R-HSA-70171 | 0.00359485582679 | 1.0 | PFKM PFKL | Glycolysis |
| WP:WP481 | 0.00438938066897 | 1.0 | PFKM PFKL | Insulin Signaling |
| GO:0070061 | 0.00450823411379 | 1.0 | PFKM PFKL | fructose binding |
| REAC:R-HSA-70326 | 0.00556574181855 | 1.0 | PFKM PFKL | Glucose metabolism |
| GO:0008443 | 0.00946729163895 | 1.0 | PFKM PFKL | phosphofructokinase activity |
| GO:0016208 | 0.0162296428096 | 1.0 | PFKM PFKL | AMP binding |
| GO:0006002 | 0.020287053512 | 1.0 | PFKM PFKL | fructose 6-phosphate metabolic process |
| GO:0030388 | 0.020287053512 | 1.0 | PFKM PFKL | fructose 1,6-bisphosphate metabolic process |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PFKL | PFKM | 0.993 | 0.918 | bioplex (PFKL) bioplex_WMM youn_WMM Malo gupta_WMM fraction treiber_WMM |
Images
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Complex HuMAP2_06807 has an average edge precision of 0.918 which is ranked 482 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PFKM | HuMAP2_02860 HuMAP2_04569 HuMAP2_05288 HuMAP2_05668 HuMAP2_06807 |
| PFKL | HuMAP2_00734 HuMAP2_01032 HuMAP2_04569 HuMAP2_05272 HuMAP2_05288 HuMAP2_05668 HuMAP2_06807 |