hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06810
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PRDX3 | Thioredoxin-dependent peroxide reductase, mitochondrial (EC 1.11.1.15) (Antioxidant protein 1) (AOP-1) (HBC189) (Peroxiredoxin III) (Prx-III) (Peroxiredoxin-3) (Protein MER5 homolog) | UniProt NCBI |
| PUS7 | Pseudouridylate synthase 7 homolog (EC 5.4.99.-) | UniProt NCBI |
| MTRR | Methionine synthase reductase (MSR) (EC 1.16.1.8) | UniProt NCBI |
| GCK | Glucokinase (EC 2.7.1.2) (Hexokinase type IV) (HK IV) (Hexokinase-4) (HK4) (Hexokinase-D) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00524 | 0.0497141369515 | 0.25 | GCK | Neomycin, kanamycin and gentamicin biosynthesis |
| REAC:R-HSA-5619073 | 0.0499190562503 | 0.25 | GCK | Defective GCK causes maturity-onset diabetes of the young 2 (MODY2) |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PRDX3 | MTRR | 0.109 | 0.375 | fraction |
| GCK | PRDX3 | 0.051 | 0.294 | fraction |
| GCK | PUS7 | 0.026 | 0.218 | fraction |
| PRDX3 | PUS7 | 0.023 | 0.211 | bioplex (PUS7) youn_WMM gupta_WMM fraction |
| PUS7 | MTRR | 0.0 | 0.008 | fraction |
Images
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Complex HuMAP2_06810 has an average edge precision of 0.221 which is ranked 5837 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PRDX3 | HuMAP2_01228 HuMAP2_05584 HuMAP2_06137 HuMAP2_06810 |
| PUS7 | HuMAP2_01877 HuMAP2_06810 |
| MTRR | HuMAP2_05584 HuMAP2_06137 HuMAP2_06810 |
| GCK | HuMAP2_00664 HuMAP2_01504 HuMAP2_03384 HuMAP2_05397 HuMAP2_05584 HuMAP2_06449 HuMAP2_06810 |