hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_06841
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| GPHN | Gephyrin [Includes: Molybdopterin adenylyltransferase (MPT adenylyltransferase) (EC 2.7.7.75) (Domain G); Molybdopterin molybdenumtransferase (MPT Mo-transferase) (EC 2.10.1.1) (Domain E)] | UniProt NCBI |
| PRPF4 | U4/U6 small nuclear ribonucleoprotein Prp4 (PRP4 homolog) (hPrp4) (U4/U6 snRNP 60 kDa protein) (WD splicing factor Prp4) | UniProt NCBI |
| SNU13 | NHP2-like protein 1 (High mobility group-like nuclear protein 2 homolog 1) (OTK27) (SNU13 homolog) (hSNU13) (U4/U6.U5 small nuclear ribonucleoprotein SNU13) (U4/U6.U5 tri-snRNP 15.5 kDa protein) [Cleaved into: NHP2-like protein 1, N-terminally processed] | UniProt NCBI |
| CCDC84 | Coiled-coil domain-containing protein 84 | UniProt NCBI |
| UTP20 | Small subunit processome component 20 homolog (Down-regulated in metastasis protein) (Novel nucleolar protein 73) (NNP73) (Protein Key-1A6) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-6790901 | 0.0237053784759 | 0.4 | UTP20 SNU13 | rRNA modification in the nucleus and cytosol |
| WP:WP411 | 0.0254557044772 | 0.4 | PRPF4 SNU13 | mRNA Processing |
| KEGG:03040 | 0.0353865382697 | 0.4 | PRPF4 SNU13 | Spliceosome |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PRPF4 | SNU13 | 0.513 | 0.632 | hein_WMM bioplex (PRPF4) bioplex_WMM youn_WMM hein (PRPF4) gupta_WMM fraction boldt_WMM |
| PRPF4 | GPHN | 0.232 | 0.47 | hein_WMM bioplex (PRPF4) bioplex_WMM youn_WMM hein (PRPF4) |
| PRPF4 | UTP20 | 0.124 | 0.395 | youn_WMM fraction |
| PRPF4 | CCDC84 | 0.106 | 0.373 | hein_WMM bioplex (CCDC84) bioplex_WMM hein (PRPF4) |
| SNU13 | CCDC84 | 0.008 | 0.09 | hein_WMM bioplex_WMM WMM_only |
| SNU13 | GPHN | 0.007 | 0.009 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| SNU13 | UTP20 | 0.007 | 0.0 | youn_WMM gupta_WMM WMM_only |
| GPHN | UTP20 | 0.007 | 0.002 | youn_WMM WMM_only |
| CCDC84 | GPHN | 0.007 | 0.005 | hein_WMM WMM_only |
Images
Click to enlarge
Complex HuMAP2_06841 has an average edge precision of 0.22 which is ranked 5862 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| GPHN | HuMAP2_04883 HuMAP2_06841 |
| PRPF4 | HuMAP2_00104 HuMAP2_00143 HuMAP2_00187 HuMAP2_00605 HuMAP2_02497 HuMAP2_04421 HuMAP2_05096 HuMAP2_06280 HuMAP2_06841 |
| SNU13 | HuMAP2_00187 HuMAP2_02226 HuMAP2_04742 HuMAP2_05096 HuMAP2_06280 HuMAP2_06560 HuMAP2_06785 HuMAP2_06841 |
| CCDC84 | HuMAP2_02578 HuMAP2_03453 HuMAP2_06841 |
| UTP20 | HuMAP2_06841 |