hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06850
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| TMEM63A | CSC1-like protein 1 (Transmembrane protein 63A) | UniProt NCBI |
| RNF13 | E3 ubiquitin-protein ligase RNF13 (EC 2.3.2.27) (RING finger protein 13) (RING-type E3 ubiquitin transferase RNF13) | UniProt NCBI |
| MFSD10 | Major facilitator superfamily domain-containing protein 10 (Tetracycline transporter-like protein) | UniProt NCBI |
| AP3S2 | AP-3 complex subunit sigma-2 (AP-3 complex subunit sigma-3B) (Adaptor-related protein complex 3 subunit sigma-2) (Sigma-3B-adaptin) (Sigma3B-adaptin) (Sigma-adaptin 3b) | UniProt NCBI |
| TYK2 | Non-receptor tyrosine-protein kinase TYK2 (EC 2.7.10.2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:2307 | 0.0499494897235 | 0.2 | AP3S2 | AP3D1-AP3S2 complex |
| CORUM:5178 | 0.0499494897235 | 0.2 | TYK2 | JAK2-PAFR-TYK2 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RNF13 | AP3S2 | 0.187 | 0.44 | bioplex (RNF13) bioplex_WMM |
| MFSD10 | TMEM63A | 0.101 | 0.362 | bioplex (TMEM63A) bioplex_WMM |
| AP3S2 | TMEM63A | 0.091 | 0.354 | bioplex (TMEM63A) bioplex_WMM |
| RNF13 | TYK2 | 0.027 | 0.228 | bioplex (RNF13) bioplex_WMM |
| AP3S2 | MFSD10 | 0.008 | 0.04 | bioplex_WMM WMM_only |
| AP3S2 | TYK2 | 0.007 | 0.001 | bioplex_WMM WMM_only |
| RNF13 | TMEM63A | 0.007 | 0.003 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_06850 has an average edge precision of 0.204 which is ranked 6127 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| TMEM63A | HuMAP2_02803 HuMAP2_04084 HuMAP2_06850 |
| RNF13 | HuMAP2_02783 HuMAP2_04084 HuMAP2_06447 HuMAP2_06850 |
| MFSD10 | HuMAP2_02803 HuMAP2_04084 HuMAP2_06850 |
| AP3S2 | HuMAP2_02783 HuMAP2_04084 HuMAP2_06447 HuMAP2_06850 |
| TYK2 | HuMAP2_05938 HuMAP2_06447 HuMAP2_06850 |