hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_06852
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PSMB9 | Proteasome subunit beta type-9 (EC 3.4.25.1) (Low molecular mass protein 2) (Macropain chain 7) (Multicatalytic endopeptidase complex chain 7) (Proteasome chain 7) (Proteasome subunit beta-1i) (Really interesting new gene 12 protein) | UniProt NCBI |
| PSMB10 | Proteasome subunit beta type-10 (EC 3.4.25.1) (Low molecular mass protein 10) (Macropain subunit MECl-1) (Multicatalytic endopeptidase complex subunit MECl-1) (Proteasome MECl-1) (Proteasome subunit beta-2i) | UniProt NCBI |
| PSME4 | Proteasome activator complex subunit 4 (Proteasome activator PA200) | UniProt NCBI |
| PSME1 | Proteasome activator complex subunit 1 (11S regulator complex subunit alpha) (REG-alpha) (Activator of multicatalytic protease subunit 1) (Interferon gamma up-regulated I-5111 protein) (IGUP I-5111) (Proteasome activator 28 subunit alpha) (PA28a) (PA28alpha) | UniProt NCBI |
| PSME2 | Proteasome activator complex subunit 2 (11S regulator complex subunit beta) (REG-beta) (Activator of multicatalytic protease subunit 2) (Proteasome activator 28 subunit beta) (PA28b) (PA28beta) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:03050 | 9.53196349159e-12 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Proteasome |
| REAC:R-HSA-1236978 | 4.19972184093e-11 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Cross-presentation of soluble exogenous antigens (endosomes) |
| REAC:R-HSA-211733 | 5.19662551024e-11 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Regulation of activated PAK-2p34 by proteasome mediated degradation |
| REAC:R-HSA-350562 | 5.76147610918e-11 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Regulation of ornithine decarboxylase (ODC) |
| REAC:R-HSA-69613 | 6.37439909952e-11 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | p53-Independent G1/S DNA damage checkpoint |
| REAC:R-HSA-69610 | 6.37439909952e-11 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | p53-Independent DNA Damage Response |
| REAC:R-HSA-349425 | 6.37439909952e-11 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Autodegradation of the E3 ubiquitin ligase COP1 |
| REAC:R-HSA-180534 | 6.37439909952e-11 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Vpu mediated degradation of CD4 |
| REAC:R-HSA-75815 | 6.37439909952e-11 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Ubiquitin-dependent degradation of Cyclin D |
| REAC:R-HSA-69601 | 6.37439909952e-11 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Ubiquitin Mediated Degradation of Phosphorylated Cdc25A |
| REAC:R-HSA-450408 | 7.03839900572e-11 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | AUF1 (hnRNP D0) binds and destabilizes mRNA |
| REAC:R-HSA-169911 | 7.03839900572e-11 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Regulation of Apoptosis |
| REAC:R-HSA-180585 | 7.03839900572e-11 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Vif-mediated degradation of APOBEC3G |
| REAC:R-HSA-8854050 | 7.7566029859e-11 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | FBXL7 down-regulates AURKA during mitotic entry and in early mitosis |
| REAC:R-HSA-174113 | 8.53226328449e-11 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | SCF-beta-TrCP mediated degradation of Emi1 |
| REAC:R-HSA-5362768 | 8.53226328449e-11 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Hh mutants that don't undergo autocatalytic processing are degraded by ERAD |
| REAC:R-HSA-4641257 | 8.53226328449e-11 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Degradation of AXIN |
| REAC:R-HSA-351202 | 1.02696019623e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Metabolism of polyamines |
| REAC:R-HSA-5387390 | 1.02696019623e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Hh mutants abrogate ligand secretion |
| REAC:R-HSA-69541 | 1.02696019623e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Stabilization of p53 |
| REAC:R-HSA-4641258 | 1.02696019623e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Degradation of DVL |
| REAC:R-HSA-5610780 | 1.22790279228e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Degradation of GLI1 by the proteasome |
| REAC:R-HSA-68827 | 1.22790279228e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | CDT1 association with the CDC6:ORC:origin complex |
| REAC:R-HSA-5676590 | 1.22790279228e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | NIK-->noncanonical NF-kB signaling |
| REAC:R-HSA-5610785 | 1.33953031885e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | GLI3 is processed to GLI3R by the proteasome |
| REAC:R-HSA-5610783 | 1.33953031885e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Degradation of GLI2 by the proteasome |
| REAC:R-HSA-5678895 | 1.33953031885e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Defective CFTR causes cystic fibrosis |
| REAC:R-HSA-5607761 | 1.33953031885e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Dectin-1 mediated noncanonical NF-kB signaling |
| REAC:R-HSA-5358346 | 1.58712520861e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Hedgehog ligand biogenesis |
| REAC:R-HSA-4608870 | 1.72394634729e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Asymmetric localization of PCP proteins |
| REAC:R-HSA-1234176 | 2.02588045331e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha |
| REAC:R-HSA-69580 | 2.19193622817e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | p53-Dependent G1/S DNA damage checkpoint |
| REAC:R-HSA-69563 | 2.19193622817e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | p53-Dependent G1 DNA Damage Response |
| REAC:R-HSA-174154 | 2.19193622817e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | APC/C:Cdc20 mediated degradation of Securin |
| REAC:R-HSA-8939902 | 2.19193622817e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Regulation of RUNX2 expression and activity |
| REAC:R-HSA-1169091 | 2.19193622817e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Activation of NF-kappaB in B cells |
| REAC:R-HSA-5658442 | 2.36870527883e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Regulation of RAS by GAPs |
| REAC:R-HSA-68867 | 2.55669776128e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Assembly of the pre-replicative complex |
| REAC:R-HSA-69615 | 2.55669776128e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | G1/S DNA Damage Checkpoints |
| REAC:R-HSA-8948751 | 2.55669776128e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Regulation of PTEN stability and activity |
| REAC:R-HSA-68949 | 3.19335796647e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Orc1 removal from chromatin |
| REAC:R-HSA-174178 | 3.19335796647e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 |
| REAC:R-HSA-69017 | 3.19335796647e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | CDK-mediated phosphorylation and removal of Cdc6 |
| REAC:R-HSA-174184 | 3.19335796647e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Cdc20:Phospho-APC/C mediated degradation of Cyclin A |
| REAC:R-HSA-179419 | 3.43166826248e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint |
| REAC:R-HSA-176409 | 3.95095310186e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | APC/C:Cdc20 mediated degradation of mitotic proteins |
| REAC:R-HSA-1234174 | 3.95095310186e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Cellular response to hypoxia |
| REAC:R-HSA-176814 | 4.2331640377e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins |
| REAC:R-HSA-2871837 | 4.5312741812e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | FCERI mediated NF-kB activation |
| REAC:R-HSA-5619084 | 4.5312741812e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | ABC transporter disorders |
| REAC:R-HSA-8852276 | 4.5312741812e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | The role of GTSE1 in G2/M progression after G2 checkpoint |
| REAC:R-HSA-1168372 | 4.84594599934e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Downstream signaling events of B Cell Receptor (BCR) |
| REAC:R-HSA-176408 | 5.52771552165e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Regulation of APC/C activators between G1/S and early anaphase |
| REAC:R-HSA-5632684 | 5.89622988976e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Hedgehog 'on' state |
| REAC:R-HSA-195253 | 6.69220077371e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Degradation of beta-catenin by the destruction complex |
| REAC:R-HSA-1236974 | 6.69220077371e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | ER-Phagosome pathway |
| REAC:R-HSA-450531 | 7.57189610424e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Regulation of mRNA stability by proteins that bind AU-rich elements |
| REAC:R-HSA-5668541 | 8.04513961076e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | TNFR2 non-canonical NF-kB pathway |
| REAC:R-HSA-453276 | 8.04513961076e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Regulation of mitotic cell cycle |
| REAC:R-HSA-69002 | 8.04513961076e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | DNA Replication Pre-Initiation |
| REAC:R-HSA-174143 | 8.04513961076e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | APC/C-mediated degradation of cell cycle proteins |
| REAC:R-HSA-5687128 | 9.06259177472e-10 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | MAPK6/MAPK4 signaling |
| REAC:R-HSA-202424 | 1.01804674096e-09 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Downstream TCR signaling |
| REAC:R-HSA-69052 | 1.01804674096e-09 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Switching of origins to a post-replicative state |
| REAC:R-HSA-4086400 | 1.14060229938e-09 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | PCP/CE pathway |
| REAC:R-HSA-5607764 | 1.20615415566e-09 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | CLEC7A (Dectin-1) signaling |
| REAC:R-HSA-1236975 | 1.34629719469e-09 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Antigen processing-Cross presentation |
| REAC:R-HSA-9020702 | 1.58065024992e-09 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Interleukin-1 signaling |
| REAC:R-HSA-382556 | 1.7542288635e-09 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | ABC-family proteins mediated transport |
| REAC:R-HSA-5689603 | 1.84655669842e-09 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | UCH proteinases |
| REAC:R-HSA-983705 | 1.94273152647e-09 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Signaling by the B Cell Receptor (BCR) |
| REAC:R-HSA-8878166 | 2.25553992627e-09 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Transcriptional regulation by RUNX2 |
| REAC:R-HSA-202403 | 2.60740152746e-09 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | TCR signaling |
| REAC:R-HSA-5610787 | 3.14346120329e-09 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Hedgehog 'off' state |
| REAC:R-HSA-69239 | 4.29128105718e-09 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Synthesis of DNA |
| REAC:R-HSA-2454202 | 4.67425579683e-09 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Fc epsilon receptor (FCERI) signaling |
| REAC:R-HSA-162909 | 5.08409696971e-09 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Host Interactions of HIV factors |
| REAC:R-HSA-446652 | 5.98998307108e-09 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Interleukin-1 family signaling |
| REAC:R-HSA-69306 | 5.98998307108e-09 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | DNA Replication |
| REAC:R-HSA-5621481 | 5.98998307108e-09 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | C-type lectin receptors (CLRs) |
| REAC:R-HSA-8939236 | 5.98998307108e-09 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | RUNX1 regulates transcription of genes involved in differentiation of HSCs |
| REAC:R-HSA-6807070 | 8.50342419088e-09 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | PTEN Regulation |
| REAC:R-HSA-3858494 | 9.16237563755e-09 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Beta-catenin independent WNT signaling |
| REAC:R-HSA-5358351 | 1.09897493916e-08 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Signaling by Hedgehog |
| REAC:R-HSA-5619115 | 1.76998850425e-08 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Disorders of transmembrane transporters |
| REAC:R-HSA-69242 | 1.94925460906e-08 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | S Phase |
| REAC:R-HSA-69481 | 2.49918476895e-08 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | G2/M Checkpoints |
| REAC:R-HSA-9010553 | 2.57584687842e-08 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Regulation of expression of SLITs and ROBOs |
| GO:0000502 | 2.59070539729e-08 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | proteasome complex |
| REAC:R-HSA-109581 | 2.65437879545e-08 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Apoptosis |
| GO:1905369 | 2.84977593702e-08 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | endopeptidase complex |
| REAC:R-HSA-5357801 | 2.90153540726e-08 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Programmed Cell Death |
| GO:0006521 | 3.12916573477e-08 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | regulation of cellular amino acid metabolic process |
| REAC:R-HSA-2467813 | 3.96994964557e-08 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Separation of Sister Chromatids |
| GO:0033238 | 4.47403126496e-08 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | regulation of cellular amine metabolic process |
| WP:WP183 | 4.70072506763e-08 | 0.8 | PSMB9 PSMB10 PSME1 PSME2 | Proteasome Degradation |
| REAC:R-HSA-69275 | 4.79939190575e-08 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | G2/M Transition |
| REAC:R-HSA-68882 | 4.9284078172e-08 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Mitotic Anaphase |
| REAC:R-HSA-5689880 | 5.06018342728e-08 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Ub-specific processing proteases |
| REAC:R-HSA-453274 | 5.06018342728e-08 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Mitotic G2-G2/M phases |
| REAC:R-HSA-2555396 | 5.06018342728e-08 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Mitotic Metaphase and Anaphase |
| REAC:R-HSA-5673001 | 5.33219036036e-08 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | RAF/MAP kinase cascade |
| REAC:R-HSA-5684996 | 6.06364245636e-08 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | MAPK1/MAPK3 signaling |
| REAC:R-HSA-9607240 | 8.14967192706e-08 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | FLT3 Signaling |
| GO:1902036 | 8.53937052267e-08 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | regulation of hematopoietic stem cell differentiation |
| REAC:R-HSA-376176 | 8.54716149986e-08 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Signaling by ROBO receptors |
| REAC:R-HSA-8878171 | 9.83356432349e-08 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Transcriptional regulation by RUNX1 |
| REAC:R-HSA-201681 | 1.05323903619e-07 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | TCF dependent signaling in response to WNT |
| REAC:R-HSA-8951664 | 1.05323903619e-07 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Neddylation |
| REAC:R-HSA-8941858 | 1.06659036688e-07 | 0.8 | PSMB9 PSMB10 PSME1 PSME2 | Regulation of RUNX3 expression and activity |
| REAC:R-HSA-9604323 | 1.06659036688e-07 | 0.8 | PSMB9 PSMB10 PSME1 PSME2 | Negative regulation of NOTCH4 signaling |
| REAC:R-HSA-162906 | 1.07739589482e-07 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | HIV Infection |
| REAC:R-HSA-1257604 | 1.12703929222e-07 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | PIP3 activates AKT signaling |
| GO:0002479 | 1.14617719967e-07 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent |
| REAC:R-HSA-449836 | 1.17849597997e-07 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Other interleukin signaling |
| GO:1905368 | 1.23045493494e-07 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | peptidase complex |
| GO:0060218 | 1.31961833602e-07 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | hematopoietic stem cell differentiation |
| GO:0061418 | 1.41387678859e-07 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | regulation of transcription from RNA polymerase II promoter in response to hypoxia |
| GO:0042590 | 1.41387678859e-07 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | antigen processing and presentation of exogenous peptide antigen via MHC class I |
| REAC:R-HSA-5683057 | 1.43383123897e-07 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | MAPK family signaling cascades |
| REAC:R-HSA-187577 | 1.65722225947e-07 | 0.8 | PSMB9 PSMB10 PSME1 PSME2 | SCF(Skp2)-mediated degradation of p27/p21 |
| GO:1901532 | 1.72940527637e-07 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | regulation of hematopoietic progenitor cell differentiation |
| GO:0031145 | 1.96934078318e-07 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | anaphase-promoting complex-dependent catabolic process |
| REAC:R-HSA-174084 | 2.03091825402e-07 | 0.8 | PSMB9 PSMB10 PSME1 PSME2 | Autodegradation of Cdh1 by Cdh1:APC/C |
| GO:0010972 | 2.37847679293e-07 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | negative regulation of G2/M transition of mitotic cell cycle |
| REAC:R-HSA-9006925 | 2.47530699312e-07 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Intracellular signaling by second messengers |
| REAC:R-HSA-5688426 | 2.62087849191e-07 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Deubiquitination |
| GO:0031146 | 3.02690565276e-07 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process |
| GO:0060071 | 3.60029235685e-07 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Wnt signaling pathway, planar cell polarity pathway |
| GO:0002474 | 3.80961167992e-07 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | antigen processing and presentation of peptide antigen via MHC class I |
| GO:0090175 | 3.80961167992e-07 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | regulation of establishment of planar polarity |
| REAC:R-HSA-69620 | 3.84287249539e-07 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Cell Cycle Checkpoints |
| REAC:R-HSA-983168 | 4.19201259121e-07 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Antigen processing: Ubiquitination & Proteasome degradation |
| GO:2000736 | 4.49663263026e-07 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | regulation of stem cell differentiation |
| GO:0070498 | 4.74644555417e-07 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | interleukin-1-mediated signaling pathway |
| GO:1902750 | 4.74644555417e-07 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | negative regulation of cell cycle G2/M phase transition |
| GO:0007164 | 5.00723926593e-07 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | establishment of tissue polarity |
| GO:0001736 | 5.00723926593e-07 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | establishment of planar polarity |
| GO:0002244 | 5.27937183473e-07 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | hematopoietic progenitor cell differentiation |
| REAC:R-HSA-9013694 | 5.46506807907e-07 | 0.8 | PSMB9 PSMB10 PSME1 PSME2 | Signaling by NOTCH4 |
| GO:0044106 | 5.56320903015e-07 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | cellular amine metabolic process |
| REAC:R-HSA-195721 | 5.66485895677e-07 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Signaling by WNT |
| REAC:R-HSA-69202 | 6.36085103797e-07 | 0.8 | PSMB9 PSMB10 PSME1 PSME2 | Cyclin E associated events during G1/S transition |
| GO:0002223 | 6.82319357151e-07 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | stimulatory C-type lectin receptor signaling pathway |
| GO:0038095 | 6.82319357151e-07 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Fc-epsilon receptor signaling pathway |
| REAC:R-HSA-69656 | 7.01630822759e-07 | 0.8 | PSMB9 PSMB10 PSME1 PSME2 | Cyclin A:Cdk2-associated events at S phase entry |
| GO:0002220 | 7.1713156925e-07 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | innate immune response activating cell surface receptor signaling pathway |
| GO:0009308 | 7.91017852143e-07 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | amine metabolic process |
| GO:0043618 | 8.30177151754e-07 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | regulation of transcription from RNA polymerase II promoter in response to stress |
| REAC:R-HSA-5663202 | 8.62309350058e-07 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Diseases of signal transduction |
| GO:0001738 | 9.57048775295e-07 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | morphogenesis of a polarized epithelium |
| REAC:R-HSA-8878159 | 1.01560921166e-06 | 0.8 | PSMB9 PSMB10 PSME1 PSME2 | Transcriptional regulation by RUNX3 |
| REAC:R-HSA-71291 | 1.02822402968e-06 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Metabolism of amino acids and derivatives |
| REAC:R-HSA-983169 | 1.02822402968e-06 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Class I MHC mediated antigen processing & presentation |
| GO:0043620 | 1.0499160419e-06 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | regulation of DNA-templated transcription in response to stress |
| REAC:R-HSA-5663205 | 1.16866830373e-06 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Infectious disease |
| GO:0090263 | 1.31389912516e-06 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | positive regulation of canonical Wnt signaling pathway |
| REAC:R-HSA-68886 | 1.51565133528e-06 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | M Phase |
| GO:1905330 | 1.84441276827e-06 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | regulation of morphogenesis of an epithelium |
| GO:0038061 | 1.92126330028e-06 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | NIK/NF-kappaB signaling |
| REAC:R-HSA-2262752 | 2.22700035802e-06 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Cellular responses to stress |
| GO:0035567 | 2.43793950738e-06 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | non-canonical Wnt signaling pathway |
| GO:0033209 | 2.43793950738e-06 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | tumor necrosis factor-mediated signaling pathway |
| GO:0071347 | 2.43793950738e-06 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | cellular response to interleukin-1 |
| GO:0010565 | 2.53392137774e-06 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | regulation of cellular ketone metabolic process |
| GO:0071456 | 3.06023346294e-06 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | cellular response to hypoxia |
| GO:0036294 | 3.41575155137e-06 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | cellular response to decreased oxygen levels |
| GO:0030177 | 3.54133065253e-06 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | positive regulation of Wnt signaling pathway |
| GO:0090090 | 3.67057629678e-06 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | negative regulation of canonical Wnt signaling pathway |
| GO:0070555 | 3.94038719129e-06 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | response to interleukin-1 |
| REAC:R-HSA-69206 | 4.12021471894e-06 | 0.8 | PSMB9 PSMB10 PSME1 PSME2 | G1/S Transition |
| GO:2000027 | 4.22583570616e-06 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | regulation of animal organ morphogenesis |
| GO:0071453 | 5.18280243929e-06 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | cellular response to oxygen levels |
| GO:0050852 | 5.18280243929e-06 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | T cell receptor signaling pathway |
| REAC:R-HSA-8953897 | 5.54154114711e-06 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Cellular responses to external stimuli |
| GO:0043488 | 6.51051039425e-06 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | regulation of mRNA stability |
| CORUM:30 | 6.70868171695e-06 | 0.4 | PSME2 PSME1 | PA28 complex |
| REAC:R-HSA-453279 | 6.76665795869e-06 | 0.8 | PSMB9 PSMB10 PSME1 PSME2 | Mitotic G1-G1/S phases |
| REAC:R-HSA-449147 | 6.91462379682e-06 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Signaling by Interleukins |
| GO:0030178 | 6.93592836046e-06 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | negative regulation of Wnt signaling pathway |
| REAC:R-HSA-422475 | 7.12122313763e-06 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Axon guidance |
| GO:0038093 | 7.15681779869e-06 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Fc receptor signaling pathway |
| REAC:R-HSA-69278 | 7.33273154143e-06 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Cell Cycle, Mitotic |
| GO:0002478 | 7.3832993746e-06 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | antigen processing and presentation of exogenous peptide antigen |
| GO:0043487 | 7.3832993746e-06 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | regulation of RNA stability |
| GO:0019884 | 7.85346230647e-06 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | antigen processing and presentation of exogenous antigen |
| GO:0048863 | 7.85346230647e-06 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | stem cell differentiation |
| GO:1990111 | 9.08002798436e-06 | 0.6 | PSMB9 PSMB10 PSME4 | spermatoproteasome complex |
| GO:0048002 | 9.97955469656e-06 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | antigen processing and presentation of peptide antigen |
| GO:0042180 | 1.08862772638e-05 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | cellular ketone metabolic process |
| GO:0010389 | 1.08862772638e-05 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | regulation of G2/M transition of mitotic cell cycle |
| GO:0061013 | 1.15265173905e-05 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | regulation of mRNA catabolic process |
| GO:0071356 | 1.21965317019e-05 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | cellular response to tumor necrosis factor |
| GO:0050851 | 1.43956026192e-05 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | antigen receptor-mediated signaling pathway |
| GO:0001666 | 1.47910862076e-05 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | response to hypoxia |
| REAC:R-HSA-382551 | 1.5893100498e-05 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Transport of small molecules |
| GO:0036293 | 1.60299689652e-05 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | response to decreased oxygen levels |
| GO:1902749 | 1.69010126471e-05 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | regulation of cell cycle G2/M phase transition |
| REAC:R-HSA-1640170 | 1.81282652788e-05 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Cell Cycle |
| GO:0034612 | 1.82781872721e-05 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | response to tumor necrosis factor |
| GO:0019882 | 1.82781872721e-05 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | antigen processing and presentation |
| GO:1901991 | 1.9743707367e-05 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | negative regulation of mitotic cell cycle phase transition |
| GO:0070482 | 2.18424105376e-05 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | response to oxygen levels |
| REAC:R-HSA-1280218 | 2.29940671928e-05 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Adaptive Immune System |
| REAC:R-HSA-8953854 | 2.37148320446e-05 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Metabolism of RNA |
| GO:1901988 | 2.72199042364e-05 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | negative regulation of cell cycle phase transition |
| GO:0060828 | 3.06355953968e-05 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | regulation of canonical Wnt signaling pathway |
| REAC:R-HSA-1280215 | 3.15061991054e-05 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Cytokine Signaling in Immune system |
| REAC:R-HSA-157118 | 3.42796697132e-05 | 0.8 | PSMB9 PSMB10 PSME1 PSME2 | Signaling by NOTCH |
| GO:0000086 | 3.68065987521e-05 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | G2/M transition of mitotic cell cycle |
| GO:0002758 | 5.43529830807e-05 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | innate immune response-activating signal transduction |
| GO:0044839 | 5.43529830807e-05 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | cell cycle G2/M phase transition |
| GO:0016579 | 5.78361624972e-05 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | protein deubiquitination |
| GO:0060070 | 6.40365569743e-05 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | canonical Wnt signaling pathway |
| GO:0002218 | 7.95557043395e-05 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | activation of innate immune response |
| GO:0070646 | 7.95557043395e-05 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | protein modification by small protein removal |
| GO:0045930 | 9.09038692953e-05 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | negative regulation of mitotic cell cycle |
| GO:0000209 | 9.61471171118e-05 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | protein polyubiquitination |
| GO:0030111 | 9.79476249228e-05 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | regulation of Wnt signaling pathway |
| GO:0002009 | 0.000103511588888 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | morphogenesis of an epithelium |
| REAC:R-HSA-168249 | 0.000117373721654 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Innate Immune System |
| GO:0002429 | 0.000117480919 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | immune response-activating cell surface receptor signaling pathway |
| GO:0010948 | 0.000126115844807 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | negative regulation of cell cycle process |
| GO:1903311 | 0.000126115844807 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | regulation of mRNA metabolic process |
| REAC:R-HSA-1266738 | 0.000133977970678 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Developmental Biology |
| GO:0006520 | 0.000144908434789 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | cellular amino acid metabolic process |
| GO:1903706 | 0.000155109589057 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | regulation of hemopoiesis |
| GO:0045089 | 0.000155109589057 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | positive regulation of innate immune response |
| REAC:R-HSA-1643685 | 0.000155670343335 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Disease |
| GO:0062012 | 0.000163131011264 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | regulation of small molecule metabolic process |
| GO:0002768 | 0.000168660501172 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | immune response-regulating cell surface receptor signaling pathway |
| GO:0002833 | 0.000186154574815 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | positive regulation of response to biotic stimulus |
| REAC:R-HSA-212436 | 0.000239251603487 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Generic Transcription Pathway |
| GO:0043687 | 0.000259151609636 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | post-translational protein modification |
| GO:0006402 | 0.000288011322919 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | mRNA catabolic process |
| GO:1901990 | 0.000338506670814 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | regulation of mitotic cell cycle phase transition |
| GO:0045088 | 0.000353438766553 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | regulation of innate immune response |
| GO:0048729 | 0.000358531544169 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | tissue morphogenesis |
| GO:0031349 | 0.000374163118691 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | positive regulation of defense response |
| REAC:R-HSA-73857 | 0.000412889072144 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | RNA Polymerase II Transcription |
| GO:0043161 | 0.000418527715825 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | proteasome-mediated ubiquitin-dependent protein catabolic process |
| GO:0016055 | 0.000424356792647 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Wnt signaling pathway |
| GO:0006401 | 0.000442234784145 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | RNA catabolic process |
| GO:0198738 | 0.000448326172357 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | cell-cell signaling by wnt |
| GO:1901987 | 0.0004797982371 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | regulation of cell cycle phase transition |
| GO:0002831 | 0.000584960883363 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | regulation of response to biotic stimulus |
| GO:1905114 | 0.000639961088829 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | cell surface receptor signaling pathway involved in cell-cell signaling |
| REAC:R-HSA-597592 | 0.000641406598892 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Post-translational protein modification |
| REAC:R-HSA-74160 | 0.000713316403356 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Gene expression (Transcription) |
| GO:0002757 | 0.000781283109288 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | immune response-activating signal transduction |
| CORUM:192 | 0.000803529153956 | 0.4 | PSME2 PSME1 | PA28-20S proteasome |
| GO:0010498 | 0.000810360313539 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | proteasomal protein catabolic process |
| GO:0043902 | 0.000881581813453 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | positive regulation of multi-organism process |
| GO:0032103 | 0.000957725180817 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | positive regulation of response to external stimulus |
| GO:0002764 | 0.0010152652871 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | immune response-regulating signaling pathway |
| GO:0034655 | 0.00136074102749 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | nucleobase-containing compound catabolic process |
| GO:0010499 | 0.00139593056214 | 0.6 | PSMB9 PSMB10 PSME4 | proteasomal ubiquitin-independent protein catabolic process |
| GO:0044772 | 0.00151627970582 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | mitotic cell cycle phase transition |
| GO:0002253 | 0.00161622147941 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | activation of immune response |
| GO:0006511 | 0.00177594994385 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | ubiquitin-dependent protein catabolic process |
| GO:0030097 | 0.00177594994385 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | hemopoiesis |
| GO:0019941 | 0.00185087474313 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | modification-dependent protein catabolic process |
| GO:0010608 | 0.0019087106243 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | posttranscriptional regulation of gene expression |
| GO:0045786 | 0.00194806448895 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | negative regulation of cell cycle |
| GO:0046700 | 0.00196798334876 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | heterocycle catabolic process |
| GO:0044270 | 0.0019880648115 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | cellular nitrogen compound catabolic process |
| GO:0048534 | 0.00200830987068 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | hematopoietic or lymphoid organ development |
| GO:0043632 | 0.00207003662248 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | modification-dependent macromolecule catabolic process |
| GO:0044770 | 0.00209094608332 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | cell cycle phase transition |
| GO:0009887 | 0.00209094608332 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | animal organ morphogenesis |
| GO:0019439 | 0.0022420910868 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | aromatic compound catabolic process |
| GO:0031347 | 0.00226437827454 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | regulation of defense response |
| GO:0016504 | 0.00235581550516 | 0.6 | PSME4 PSME1 PSME2 | peptidase activator activity |
| GO:0007346 | 0.00244913233484 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | regulation of mitotic cell cycle |
| GO:1901361 | 0.0027226606524 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | organic cyclic compound catabolic process |
| GO:0002520 | 0.00274868991294 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | immune system development |
| REAC:R-HSA-168256 | 0.00339317023665 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Immune System |
| GO:0019221 | 0.00359470075026 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | cytokine-mediated signaling pathway |
| GO:0050778 | 0.00382718608595 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | positive regulation of immune response |
| GO:0045087 | 0.00393043223656 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | innate immune response |
| REAC:R-HSA-392499 | 0.0039377533293 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Metabolism of proteins |
| GO:0016567 | 0.00400049209339 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | protein ubiquitination |
| GO:0051603 | 0.0041074517567 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | proteolysis involved in cellular protein catabolic process |
| CORUM:193 | 0.00420720259224 | 0.4 | PSME2 PSME1 | PA700-20S-PA28 complex |
| GO:0043900 | 0.00444212952461 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | regulation of multi-organism process |
| REAC:R-HSA-1430728 | 0.00473657209702 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Metabolism |
| GO:0010564 | 0.00544233743161 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | regulation of cell cycle process |
| REAC:R-HSA-162582 | 0.00595743543191 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | Signal Transduction |
| KEGG:04612 | 0.00610128129602 | 0.4 | PSME2 PSME1 | Antigen processing and presentation |
| GO:0044257 | 0.00640677563005 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | cellular protein catabolic process |
| GO:0000165 | 0.00661510979699 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | MAPK cascade |
| GO:0032446 | 0.00732992354676 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | protein modification by small protein conjugation |
| GO:0023014 | 0.00798187083116 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | signal transduction by protein phosphorylation |
| GO:0060429 | 0.0084845135814 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | epithelium development |
| GO:0098542 | 0.00874515634985 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | defense response to other organism |
| GO:0071345 | 0.00928565736249 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | cellular response to cytokine stimulus |
| GO:0031329 | 0.00928565736249 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | regulation of cellular catabolic process |
| GO:0022603 | 0.00956574885851 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | regulation of anatomical structure morphogenesis |
| GO:0009628 | 0.0103710049276 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | response to abiotic stimulus |
| GO:0032101 | 0.0113916415466 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | regulation of response to external stimulus |
| GO:0050776 | 0.012058619765 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | regulation of immune response |
| GO:0016071 | 0.0124036237668 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | mRNA metabolic process |
| GO:1903047 | 0.0124910964308 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | mitotic cell cycle process |
| GO:0002684 | 0.0130263542754 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | positive regulation of immune system process |
| GO:0034097 | 0.0137684122182 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | response to cytokine |
| GO:0030163 | 0.0138634979379 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | protein catabolic process |
| GO:0009894 | 0.0197094416222 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | regulation of catabolic process |
| GO:0070647 | 0.023802724014 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | protein modification by small protein conjugation or removal |
| GO:0051707 | 0.0240980404598 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | response to other organism |
| GO:0043207 | 0.0240980404598 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | response to external biotic stimulus |
| GO:0019752 | 0.0246974667253 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | carboxylic acid metabolic process |
| GO:0009968 | 0.0259321029285 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | negative regulation of signal transduction |
| GO:0009607 | 0.02689008569 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | response to biotic stimulus |
| GO:0000278 | 0.02689008569 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | mitotic cell cycle |
| GO:0010648 | 0.032678035432 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | negative regulation of cell communication |
| GO:0023057 | 0.0334424029162 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | negative regulation of signaling |
| GO:0043436 | 0.0374817807184 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | oxoacid metabolic process |
| GO:0055085 | 0.039642806516 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | transmembrane transport |
| GO:0051726 | 0.0398642747089 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | regulation of cell cycle |
| GO:0006082 | 0.0403101804931 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | organic acid metabolic process |
| GO:0061133 | 0.0450641792523 | 0.4 | PSME2 PSME1 | endopeptidase activator activity |
| GO:0006952 | 0.0457310141551 | 1.0 | PSMB9 PSME2 PSMB10 PSME1 PSME4 | defense response |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PSME2 | PSMB9 | 0.965 | 0.874 | bioplex (PSMB9) bioplex_WMM |
| PSMB9 | PSMB10 | 0.905 | 0.828 | bioplex (PSMB9) bioplex_WMM fraction |
| PSME1 | PSMB9 | 0.836 | 0.78 | bioplex (PSMB9) bioplex_WMM |
| PSME4 | PSMB9 | 0.835 | 0.78 | bioplex (PSMB9) bioplex_WMM |
| PSME1 | PSME2 | 0.041 | 0.27 | hein_WMM bioplex_WMM WMM_only treiber_WMM |
| PSME2 | PSME4 | 0.021 | 0.195 | hein_WMM bioplex_WMM WMM_only |
| PSME1 | PSME4 | 0.018 | 0.179 | hein_WMM bioplex_WMM WMM_only |
| PSME4 | PSMB10 | 0.01 | 0.097 | bioplex_WMM WMM_only |
| PSME2 | PSMB10 | 0.009 | 0.109 | bioplex_WMM WMM_only |
| PSME1 | PSMB10 | 0.009 | 0.105 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_06852 has an average edge precision of 0.422 which is ranked 3095 out of all 6965 complexes.
Related Complexes