hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06867
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SEPTIN2 | Septin-2 (Neural precursor cell expressed developmentally down-regulated protein 5) (NEDD-5) | UniProt NCBI |
| SEPTIN1 | Septin-1 (LARP) (Peanut-like protein 3) (Serologically defined breast cancer antigen NY-BR-24) | UniProt NCBI |
| SEPTIN6 | Septin-6 | UniProt NCBI |
| SEPTIN9 | Septin-9 (MLL septin-like fusion protein MSF-A) (MLL septin-like fusion protein) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1) | UniProt NCBI |
| SEPTIN7 | Septin-7 (CDC10 protein homolog) | UniProt NCBI |
| SEPTIN3 | Neuronal-specific septin-3 | UniProt NCBI |
| SEPTIN14 | Septin-14 | UniProt NCBI |
| SEPTIN10 | Septin-10 | UniProt NCBI |
| SEPTIN11 | Septin-11 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0032156 | 1.00958964926e-24 | 1.0 | SEPTIN10 SEPTIN2 SEPTIN6 SEPTIN14 SEPTIN1 SEPTIN7 SEPTIN9 SEPTIN3 SEPTIN11 | septin cytoskeleton |
| GO:0031105 | 1.00958964926e-24 | 1.0 | SEPTIN10 SEPTIN2 SEPTIN6 SEPTIN14 SEPTIN1 SEPTIN7 SEPTIN9 SEPTIN3 SEPTIN11 | septin complex |
| GO:0005940 | 1.00958964926e-24 | 1.0 | SEPTIN10 SEPTIN2 SEPTIN6 SEPTIN14 SEPTIN1 SEPTIN7 SEPTIN9 SEPTIN3 SEPTIN11 | septin ring |
| GO:0061640 | 4.3810489625e-16 | 1.0 | SEPTIN10 SEPTIN2 SEPTIN6 SEPTIN14 SEPTIN1 SEPTIN7 SEPTIN9 SEPTIN3 SEPTIN11 | cytoskeleton-dependent cytokinesis |
| GO:0044448 | 1.80653240476e-14 | 1.0 | SEPTIN10 SEPTIN2 SEPTIN6 SEPTIN14 SEPTIN1 SEPTIN7 SEPTIN9 SEPTIN3 SEPTIN11 | cell cortex part |
| GO:0000910 | 4.18294440924e-14 | 1.0 | SEPTIN10 SEPTIN2 SEPTIN6 SEPTIN14 SEPTIN1 SEPTIN7 SEPTIN9 SEPTIN3 SEPTIN11 | cytokinesis |
| GO:0005938 | 5.40489321922e-13 | 1.0 | SEPTIN10 SEPTIN2 SEPTIN6 SEPTIN14 SEPTIN1 SEPTIN7 SEPTIN9 SEPTIN3 SEPTIN11 | cell cortex |
| GO:0051301 | 8.12953891845e-13 | 1.0 | SEPTIN10 SEPTIN2 SEPTIN6 SEPTIN14 SEPTIN1 SEPTIN7 SEPTIN9 SEPTIN3 SEPTIN11 | cell division |
| GO:0003924 | 3.95397194055e-12 | 1.0 | SEPTIN10 SEPTIN2 SEPTIN6 SEPTIN14 SEPTIN1 SEPTIN7 SEPTIN9 SEPTIN3 SEPTIN11 | GTPase activity |
| CORUM:1345 | 1.26984090249e-11 | 0.444444444444 | SEPTIN9 SEPTIN11 SEPTIN7 SEPTIN2 | Septin complex |
| GO:0099568 | 2.27978038578e-11 | 1.0 | SEPTIN10 SEPTIN2 SEPTIN6 SEPTIN14 SEPTIN1 SEPTIN7 SEPTIN9 SEPTIN3 SEPTIN11 | cytoplasmic region |
| KEGG:05100 | 4.77593604752e-11 | 0.666666666667 | SEPTIN11 SEPTIN6 SEPTIN1 SEPTIN9 SEPTIN3 SEPTIN2 | Bacterial invasion of epithelial cells |
| GO:0017111 | 9.10840264264e-09 | 1.0 | SEPTIN10 SEPTIN2 SEPTIN6 SEPTIN14 SEPTIN1 SEPTIN7 SEPTIN9 SEPTIN3 SEPTIN11 | nucleoside-triphosphatase activity |
| GO:0016462 | 1.67357737581e-08 | 1.0 | SEPTIN10 SEPTIN2 SEPTIN6 SEPTIN14 SEPTIN1 SEPTIN7 SEPTIN9 SEPTIN3 SEPTIN11 | pyrophosphatase activity |
| GO:0016818 | 1.72344950432e-08 | 1.0 | SEPTIN10 SEPTIN2 SEPTIN6 SEPTIN14 SEPTIN1 SEPTIN7 SEPTIN9 SEPTIN3 SEPTIN11 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides |
| GO:0016817 | 1.72344950432e-08 | 1.0 | SEPTIN10 SEPTIN2 SEPTIN6 SEPTIN14 SEPTIN1 SEPTIN7 SEPTIN9 SEPTIN3 SEPTIN11 | hydrolase activity, acting on acid anhydrides |
| GO:0015630 | 7.16216154992e-07 | 1.0 | SEPTIN10 SEPTIN2 SEPTIN6 SEPTIN14 SEPTIN1 SEPTIN7 SEPTIN9 SEPTIN3 SEPTIN11 | microtubule cytoskeleton |
| GO:0022402 | 3.04319367458e-06 | 1.0 | SEPTIN10 SEPTIN2 SEPTIN6 SEPTIN14 SEPTIN1 SEPTIN7 SEPTIN9 SEPTIN3 SEPTIN11 | cell cycle process |
| GO:0044430 | 6.40285487113e-06 | 1.0 | SEPTIN10 SEPTIN2 SEPTIN6 SEPTIN14 SEPTIN1 SEPTIN7 SEPTIN9 SEPTIN3 SEPTIN11 | cytoskeletal part |
| GO:0007049 | 1.43335920592e-05 | 1.0 | SEPTIN10 SEPTIN2 SEPTIN6 SEPTIN14 SEPTIN1 SEPTIN7 SEPTIN9 SEPTIN3 SEPTIN11 | cell cycle |
| GO:0005856 | 4.45418003239e-05 | 1.0 | SEPTIN10 SEPTIN2 SEPTIN6 SEPTIN14 SEPTIN1 SEPTIN7 SEPTIN9 SEPTIN3 SEPTIN11 | cytoskeleton |
| GO:0097227 | 7.62415024416e-05 | 0.333333333333 | SEPTIN6 SEPTIN7 SEPTIN2 | sperm annulus |
| GO:0016787 | 0.000241822208307 | 1.0 | SEPTIN10 SEPTIN2 SEPTIN6 SEPTIN14 SEPTIN1 SEPTIN7 SEPTIN9 SEPTIN3 SEPTIN11 | hydrolase activity |
| GO:0060271 | 0.0260501632141 | 0.555555555556 | SEPTIN6 SEPTIN9 SEPTIN11 SEPTIN7 SEPTIN2 | cilium assembly |
| GO:0044782 | 0.0336682235482 | 0.555555555556 | SEPTIN6 SEPTIN9 SEPTIN11 SEPTIN7 SEPTIN2 | cilium organization |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SEPTIN7 | SEPTIN10 | 1.0 | 0.949 | hein_WMM bioplex (SEPTIN10,SEPTIN7) bioplex_WMM Guru hein (SEPTIN7) Malo fraction |
| SEPTIN6 | SEPTIN7 | 1.0 | 0.949 | hein_WMM bioplex (SEPTIN6,SEPTIN7) bioplex_WMM Guru youn_WMM hein (SEPTIN6,SEPTIN7) Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| SEPTIN6 | SEPTIN2 | 1.0 | 0.949 | hein_WMM bioplex (SEPTIN2,SEPTIN6) bioplex_WMM Guru youn_WMM hein (SEPTIN2,SEPTIN6) Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| SEPTIN2 | SEPTIN10 | 1.0 | 0.949 | hein_WMM bioplex (SEPTIN10,SEPTIN2) bioplex_WMM Guru hein (SEPTIN2) Malo fraction |
| SEPTIN2 | SEPTIN11 | 1.0 | 0.949 | hein_WMM bioplex (SEPTIN2) bioplex_WMM Guru boldt youn_WMM hein (SEPTIN11,SEPTIN2) Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| SEPTIN2 | SEPTIN9 | 1.0 | 0.949 | hein_WMM bioplex (SEPTIN2) bioplex_WMM boldt youn_WMM hein (SEPTIN2,SEPTIN9) Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| SEPTIN11 | SEPTIN9 | 1.0 | 0.949 | hein_WMM bioplex_WMM boldt youn_WMM hein (SEPTIN11,SEPTIN9) Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| SEPTIN7 | SEPTIN9 | 1.0 | 0.949 | hein_WMM bioplex (SEPTIN7) bioplex_WMM boldt youn_WMM hein (SEPTIN7,SEPTIN9) Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| SEPTIN7 | SEPTIN11 | 1.0 | 0.949 | hein_WMM bioplex (SEPTIN7) bioplex_WMM Guru boldt youn_WMM hein (SEPTIN11,SEPTIN7) Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| SEPTIN7 | SEPTIN2 | 1.0 | 0.949 | hein_WMM bioplex (SEPTIN2,SEPTIN7) bioplex_WMM Guru boldt youn_WMM hein (SEPTIN2,SEPTIN7) Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| SEPTIN6 | SEPTIN9 | 1.0 | 0.949 | hein_WMM bioplex (SEPTIN6) bioplex_WMM youn_WMM hein (SEPTIN6,SEPTIN9) gupta_WMM boldt_WMM treiber_WMM |
| SEPTIN6 | SEPTIN11 | 1.0 | 0.949 | hein_WMM bioplex (SEPTIN6) bioplex_WMM youn_WMM hein (SEPTIN11) gupta_WMM boldt_WMM |
| SEPTIN6 | SEPTIN10 | 1.0 | 0.949 | hein_WMM bioplex (SEPTIN10,SEPTIN6) bioplex_WMM hein (SEPTIN6) |
| SEPTIN14 | SEPTIN3 | 1.0 | 0.949 | bioplex (SEPTIN3) bioplex_WMM |
| SEPTIN7 | SEPTIN3 | 0.999 | 0.949 | bioplex (SEPTIN3,SEPTIN7) bioplex_WMM youn_WMM gupta_WMM |
| SEPTIN10 | SEPTIN9 | 0.994 | 0.921 | hein_WMM bioplex (SEPTIN10) bioplex_WMM hein (SEPTIN9) |
| SEPTIN7 | SEPTIN14 | 0.984 | 0.899 | bioplex (SEPTIN7) bioplex_WMM |
| SEPTIN2 | SEPTIN3 | 0.983 | 0.899 | bioplex (SEPTIN2,SEPTIN3) bioplex_WMM youn_WMM gupta_WMM |
| SEPTIN11 | SEPTIN10 | 0.98 | 0.896 | hein_WMM bioplex (SEPTIN10) bioplex_WMM hein (SEPTIN11) |
| SEPTIN11 | SEPTIN3 | 0.953 | 0.859 | bioplex (SEPTIN3) bioplex_WMM youn_WMM gupta_WMM |
| SEPTIN6 | SEPTIN3 | 0.944 | 0.856 | bioplex (SEPTIN3,SEPTIN6) bioplex_WMM youn_WMM gupta_WMM |
| SEPTIN6 | SEPTIN14 | 0.938 | 0.85 | bioplex (SEPTIN6) bioplex_WMM |
| SEPTIN10 | SEPTIN3 | 0.912 | 0.836 | bioplex (SEPTIN10,SEPTIN3) bioplex_WMM |
| SEPTIN10 | SEPTIN14 | 0.832 | 0.78 | bioplex (SEPTIN10) bioplex_WMM |
| SEPTIN11 | SEPTIN1 | 0.79 | 0.758 | bioplex (SEPTIN1) bioplex_WMM |
| SEPTIN9 | SEPTIN1 | 0.716 | 0.73 | bioplex (SEPTIN1) bioplex_WMM treiber_WMM |
| SEPTIN6 | SEPTIN1 | 0.567 | 0.654 | bioplex (SEPTIN1) bioplex_WMM treiber_WMM |
| SEPTIN7 | SEPTIN1 | 0.548 | 0.642 | bioplex (SEPTIN1) bioplex_WMM |
| SEPTIN1 | SEPTIN3 | 0.46 | 0.598 | bioplex (SEPTIN1) bioplex_WMM |
| SEPTIN2 | SEPTIN1 | 0.449 | 0.592 | bioplex (SEPTIN1) bioplex_WMM |
| SEPTIN9 | SEPTIN3 | 0.418 | 0.573 | bioplex (SEPTIN3) bioplex_WMM youn_WMM gupta_WMM |
| SEPTIN10 | SEPTIN1 | 0.367 | 0.542 | bioplex (SEPTIN1) bioplex_WMM |
| SEPTIN9 | SEPTIN14 | 0.015 | 0.149 | bioplex_WMM WMM_only |
| SEPTIN2 | SEPTIN14 | 0.015 | 0.149 | bioplex_WMM WMM_only |
| SEPTIN11 | SEPTIN14 | 0.015 | 0.14 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_06867 has an average edge precision of 0.787 which is ranked 975 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SEPTIN2 | HuMAP2_03114 HuMAP2_04295 HuMAP2_04535 HuMAP2_04985 HuMAP2_06867 |
| SEPTIN1 | HuMAP2_04295 HuMAP2_04535 HuMAP2_04985 HuMAP2_06867 |
| SEPTIN6 | HuMAP2_00639 HuMAP2_03114 HuMAP2_04295 HuMAP2_04535 HuMAP2_04985 HuMAP2_06867 |
| SEPTIN9 | HuMAP2_03114 HuMAP2_04295 HuMAP2_04535 HuMAP2_04985 HuMAP2_06867 |
| SEPTIN7 | HuMAP2_03114 HuMAP2_04295 HuMAP2_04535 HuMAP2_04985 HuMAP2_06867 |
| SEPTIN3 | HuMAP2_04295 HuMAP2_04535 HuMAP2_04985 HuMAP2_06867 |
| SEPTIN14 | HuMAP2_04295 HuMAP2_04535 HuMAP2_04985 HuMAP2_06867 |
| SEPTIN10 | HuMAP2_03114 HuMAP2_04295 HuMAP2_04535 HuMAP2_04985 HuMAP2_06867 |
| SEPTIN11 | HuMAP2_03114 HuMAP2_04295 HuMAP2_04535 HuMAP2_04985 HuMAP2_06867 |