hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06882
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ACVRL1 | Serine/threonine-protein kinase receptor R3 (SKR3) (EC 2.7.11.30) (Activin receptor-like kinase 1) (ALK-1) (TGF-B superfamily receptor type I) (TSR-I) | UniProt NCBI |
| SLC8A1 | Sodium/calcium exchanger 1 (Na(+)/Ca(2+)-exchange protein 1) (Solute carrier family 8 member 1) | UniProt NCBI |
| ACVR1 | Activin receptor type-1 (EC 2.7.11.30) (Activin receptor type I) (ACTR-I) (Activin receptor-like kinase 2) (ALK-2) (Serine/threonine-protein kinase receptor R1) (SKR1) (TGF-B superfamily receptor type I) (TSR-I) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0070724 | 0.00405722906526 | 0.666666666667 | ACVR1 ACVRL1 | BMP receptor complex |
| KEGG:04060 | 0.00565620497262 | 0.666666666667 | ACVR1 ACVRL1 | Cytokine-cytokine receptor interaction |
| GO:0016361 | 0.00811409485621 | 0.666666666667 | ACVR1 ACVRL1 | activin receptor activity, type I |
| GO:0005025 | 0.0135228859698 | 0.666666666667 | ACVR1 ACVRL1 | transforming growth factor beta receptor activity, type I |
| GO:0017002 | 0.0378589948753 | 0.666666666667 | ACVR1 ACVRL1 | activin-activated receptor activity |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ACVR1 | ACVRL1 | 0.147 | 0.408 | bioplex (ACVR1) bioplex_WMM |
| ACVR1 | SLC8A1 | 0.113 | 0.383 | bioplex (ACVR1) bioplex_WMM |
| SLC8A1 | ACVRL1 | 0.008 | 0.091 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_06882 has an average edge precision of 0.294 which is ranked 4687 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ACVRL1 | HuMAP2_06404 HuMAP2_06882 |
| SLC8A1 | HuMAP2_06404 HuMAP2_06882 |
| ACVR1 | HuMAP2_01093 HuMAP2_05210 HuMAP2_06404 HuMAP2_06882 |