hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06898
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| MAPK3 | Mitogen-activated protein kinase 3 (MAP kinase 3) (MAPK 3) (EC 2.7.11.24) (ERT2) (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase isoform p44) (p44-MAPK) (Microtubule-associated protein 2 kinase) (p44-ERK1) | UniProt NCBI |
| TRMT5 | tRNA (guanine(37)-N1)-methyltransferase (EC 2.1.1.228) (M1G-methyltransferase) (tRNA [GM37] methyltransferase) (tRNA methyltransferase 5 homolog) | UniProt NCBI |
| UBA1 | Ubiquitin-like modifier-activating enzyme 1 (EC 6.2.1.45) (Protein A1S9) (Ubiquitin-activating enzyme E1) | UniProt NCBI |
| MYOF | Myoferlin (Fer-1-like protein 3) | UniProt NCBI |
| SUSD4 | Sushi domain-containing protein 4 | UniProt NCBI |
| DHPS | Deoxyhypusine synthase (DHS) (EC 2.5.1.46) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP3646 | 0.00549036558835 | 0.333333333333 | MAPK3 MYOF | Hepatitis C and Hepatocellular Carcinoma |
| CORUM:55 | 0.0499726005494 | 0.166666666667 | MAPK3 | HDAC4-ERK1 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DHPS | MAPK3 | 0.342 | 0.531 | hein_WMM bioplex_WMM hein (MAPK3) |
| SUSD4 | DHPS | 0.246 | 0.469 | bioplex (SUSD4) bioplex_WMM |
| MAPK3 | UBA1 | 0.079 | 0.353 | bioplex_WMM boldt gupta_WMM fraction boldt_WMM |
| TRMT5 | UBA1 | 0.025 | 0.214 | youn_WMM fraction |
| MYOF | UBA1 | 0.02 | 0.188 | fraction treiber_WMM |
| TRMT5 | DHPS | 0.007 | 0.002 | youn_WMM WMM_only |
| SUSD4 | UBA1 | 0.007 | 0.002 | bioplex (SUSD4) |
| DHPS | UBA1 | 0.003 | 0.014 | bioplex_WMM youn_WMM gupta_WMM fraction |
Images
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Complex HuMAP2_06898 has an average edge precision of 0.222 which is ranked 5829 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| MAPK3 | HuMAP2_01496 HuMAP2_03697 HuMAP2_06898 |
| TRMT5 | HuMAP2_00669 HuMAP2_03771 HuMAP2_06898 HuMAP2_07011 |
| UBA1 | HuMAP2_02268 HuMAP2_06898 |
| MYOF | HuMAP2_00221 HuMAP2_02063 HuMAP2_05949 HuMAP2_06898 |
| SUSD4 | HuMAP2_01255 HuMAP2_02156 HuMAP2_03697 HuMAP2_06898 |
| DHPS | HuMAP2_01255 HuMAP2_02156 HuMAP2_03697 HuMAP2_06898 |