hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06912
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| EZR | Ezrin (Cytovillin) (Villin-2) (p81) | UniProt NCBI |
| TARS1 | Threonine--tRNA ligase, cytoplasmic (EC 6.1.1.3) (Threonyl-tRNA synthetase) (ThrRS) | UniProt NCBI |
| RDX | Radixin | UniProt NCBI |
| ACAA2 | 3-ketoacyl-CoA thiolase, mitochondrial (EC 2.3.1.16) (Acetyl-CoA acetyltransferase) (EC 2.3.1.9) (Acetyl-CoA acyltransferase) (Acyl-CoA hydrolase, mitochondrial) (EC 3.1.2.-) (EC 3.1.2.1) (EC 3.1.2.2) (Beta-ketothiolase) (Mitochondrial 3-oxoacyl-CoA thiolase) (T1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-437239 | 0.00991669978918 | 0.5 | RDX EZR | Recycling pathway of L1 |
| WP:WP51 | 0.0143575098671 | 0.5 | RDX EZR | Regulation of Actin Cytoskeleton |
| KEGG:04530 | 0.0206513420529 | 0.5 | RDX EZR | Tight junction |
| KEGG:05206 | 0.0241976216174 | 0.5 | RDX EZR | MicroRNAs in cancer |
| KEGG:04810 | 0.0342711457345 | 0.5 | RDX EZR | Regulation of actin cytoskeleton |
| KEGG:05205 | 0.03463652866 | 0.5 | RDX EZR | Proteoglycans in cancer |
| GO:1902965 | 0.0405595771497 | 0.5 | RDX EZR | regulation of protein localization to early endosome |
| GO:1902966 | 0.0405595771497 | 0.5 | RDX EZR | positive regulation of protein localization to early endosome |
| GO:1905668 | 0.0405595771497 | 0.5 | RDX EZR | positive regulation of protein localization to endosome |
| CORUM:6784 | 0.0499140284799 | 0.25 | EZR | SCHIP1-EZR-NHERF2 complex |
| CORUM:6791 | 0.0499140284799 | 0.25 | EZR | NHERF1-NPT2A-EZR complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| EZR | RDX | 0.989 | 0.906 | hein_WMM bioplex_WMM youn_WMM hein (EZR) gupta_WMM treiber_WMM |
| EZR | ACAA2 | 0.748 | 0.742 | bioplex_WMM Guru gupta_WMM fraction treiber_WMM |
| ACAA2 | RDX | 0.744 | 0.74 | bioplex_WMM Guru gupta_WMM fraction |
| EZR | TARS1 | 0.518 | 0.632 | bioplex_WMM Guru boldt youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| ACAA2 | TARS1 | 0.006 | 0.003 | bioplex_WMM Guru gupta_WMM fraction |
| RDX | TARS1 | 0.005 | 0.01 | bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
Images
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Complex HuMAP2_06912 has an average edge precision of 0.505 which is ranked 2469 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| EZR | HuMAP2_02855 HuMAP2_02912 HuMAP2_04993 HuMAP2_06912 |
| TARS1 | HuMAP2_06912 |
| RDX | HuMAP2_02855 HuMAP2_02912 HuMAP2_04993 HuMAP2_06912 |
| ACAA2 | HuMAP2_02855 HuMAP2_02912 HuMAP2_04993 HuMAP2_05019 HuMAP2_06912 |