hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06914
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RDH13 | Retinol dehydrogenase 13 (EC 1.1.1.300) (Short chain dehydrogenase/reductase family 7C member 3) | UniProt NCBI |
| CHID1 | Chitinase domain-containing protein 1 (Stabilin-1-interacting chitinase-like protein) (SI-CLP) | UniProt NCBI |
| STK24 | Serine/threonine-protein kinase 24 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 3) (MST-3) (STE20-like kinase MST3) [Cleaved into: Serine/threonine-protein kinase 24 36 kDa subunit (Mammalian STE20-like protein kinase 3 N-terminal) (MST3/N); Serine/threonine-protein kinase 24 12 kDa subunit (Mammalian STE20-like protein kinase 3 C-terminal) (MST3/C)] | UniProt NCBI |
| STK26 | Serine/threonine-protein kinase 26 (EC 2.7.11.1) (MST3 and SOK1-related kinase) (Mammalian STE20-like protein kinase 4) (MST-4) (STE20-like kinase MST4) (Serine/threonine-protein kinase MASK) | UniProt NCBI |
| STK25 | Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response kinase 1) (SOK-1) (Ste20/oxidant stress response kinase 1) | UniProt NCBI |
| PDCD10 | Programmed cell death protein 10 (Cerebral cavernous malformations 3 protein) (TF-1 cell apoptosis-related protein 15) | UniProt NCBI |
| PHF1 | PHD finger protein 1 (Protein PHF1) (hPHF1) (Polycomb-like protein 1) (hPCl1) | UniProt NCBI |
| PROSER2 | Proline and serine-rich protein 2 | UniProt NCBI |
| CHMP2B | Charged multivesicular body protein 2b (CHMP2.5) (Chromatin-modifying protein 2b) (CHMP2b) (Vacuolar protein sorting-associated protein 2-2) (Vps2-2) (hVps2-2) | UniProt NCBI |
| C9orf78 | Telomere length and silencing protein 1 homolog (Hepatocellular carcinoma-associated antigen 59) | UniProt NCBI |
| C4orf19 | Uncharacterized protein C4orf19 | UniProt NCBI |
| SLC25A43 | Solute carrier family 25 member 43 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0036473 | 0.00373769465531 | 0.333333333333 | PDCD10 STK26 STK24 STK25 | cell death in response to oxidative stress |
| GO:0042542 | 0.00536745202529 | 0.333333333333 | PDCD10 STK26 STK24 STK25 | response to hydrogen peroxide |
| GO:0036474 | 0.0135004782501 | 0.25 | PDCD10 STK26 STK25 | cell death in response to hydrogen peroxide |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| STK24 | STK25 | 1.0 | 0.949 | bioplex (STK25) bioplex_WMM |
| STK24 | PDCD10 | 1.0 | 0.949 | hein_WMM bioplex (PDCD10) bioplex_WMM Malo fraction |
| STK25 | STK26 | 1.0 | 0.949 | bioplex (STK25) bioplex_WMM |
| STK26 | PDCD10 | 1.0 | 0.949 | hein_WMM bioplex (PDCD10) bioplex_WMM Malo fraction |
| STK25 | PDCD10 | 0.999 | 0.949 | bioplex (PDCD10,STK25) bioplex_WMM Malo fraction |
| STK24 | C4orf19 | 0.929 | 0.845 | bioplex (C4orf19) bioplex_WMM |
| PDCD10 | C4orf19 | 0.561 | 0.65 | bioplex (C4orf19) bioplex_WMM |
| PDCD10 | PROSER2 | 0.36 | 0.543 | bioplex (PROSER2) bioplex_WMM |
| STK24 | PROSER2 | 0.17 | 0.426 | bioplex (PROSER2) bioplex_WMM |
| STK25 | C4orf19 | 0.083 | 0.35 | bioplex (C4orf19) bioplex_WMM |
| STK26 | C4orf19 | 0.081 | 0.351 | bioplex (C4orf19) bioplex_WMM |
| C9orf78 | STK24 | 0.064 | 0.348 | fraction |
| SLC25A43 | PROSER2 | 0.06 | 0.336 | bioplex (SLC25A43) bioplex_WMM |
| CHMP2B | STK24 | 0.057 | 0.318 | gupta_WMM fraction |
| PROSER2 | RDH13 | 0.052 | 0.3 | bioplex (PROSER2) bioplex_WMM |
| STK26 | CHID1 | 0.033 | 0.247 | bioplex_WMM fraction |
| PHF1 | PROSER2 | 0.028 | 0.23 | bioplex (PROSER2) bioplex_WMM |
| STK24 | CHID1 | 0.026 | 0.218 | fraction |
| STK24 | STK26 | 0.022 | 0.2 | hein_WMM bioplex_WMM WMM_only |
| CHMP2B | CHID1 | 0.02 | 0.185 | bioplex_WMM fraction |
| STK25 | PROSER2 | 0.02 | 0.185 | bioplex (PROSER2) bioplex_WMM |
| STK26 | PROSER2 | 0.02 | 0.187 | bioplex (PROSER2) bioplex_WMM |
| CHMP2B | STK26 | 0.019 | 0.186 | youn_WMM gupta_WMM fraction |
| CHMP2B | C9orf78 | 0.015 | 0.153 | bioplex_WMM gupta_WMM fraction |
| STK26 | PHF1 | 0.008 | 0.042 | bioplex_WMM WMM_only |
| STK24 | PHF1 | 0.008 | 0.041 | bioplex_WMM WMM_only |
| STK25 | PHF1 | 0.008 | 0.028 | bioplex_WMM WMM_only |
| PDCD10 | PHF1 | 0.008 | 0.015 | bioplex_WMM WMM_only |
| PHF1 | RDH13 | 0.007 | 0.006 | bioplex_WMM WMM_only |
| STK26 | RDH13 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| STK24 | RDH13 | 0.007 | 0.005 | bioplex_WMM WMM_only |
| STK25 | RDH13 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| CHMP2B | PROSER2 | 0.007 | 0.003 | youn_WMM WMM_only |
| PDCD10 | RDH13 | 0.007 | 0.001 | bioplex_WMM WMM_only |
| CHMP2B | RDH13 | 0.007 | 0.0 | bioplex_WMM WMM_only |
| STK25 | CHID1 | 0.007 | 0.004 | WMM_only bioplex_WMM |
| CHMP2B | PDCD10 | 0.006 | 0.007 | bioplex_WMM fraction |
| CHMP2B | STK25 | 0.005 | 0.006 | fraction |
| CHID1 | RDH13 | 0.005 | 0.007 | bioplex_WMM WMM_only |
| PDCD10 | CHID1 | 0.005 | 0.006 | bioplex_WMM fraction |
| SLC25A43 | STK25 | 0.004 | 0.014 | bioplex (SLC25A43) |
| SLC25A43 | PDCD10 | 0.004 | 0.01 | bioplex (SLC25A43) |
| C9orf78 | STK25 | 0.0 | 0.01 | fraction |
| C9orf78 | PDCD10 | 0.0 | 0.001 | fraction |
| C9orf78 | STK26 | 0.0 | 0.003 | fraction |
Images
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Complex HuMAP2_06914 has an average edge precision of 0.249 which is ranked 5388 out of all 6965 complexes.
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