hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06927
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| HADH | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HCDH) (EC 1.1.1.35) (Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase) (Short-chain 3-hydroxyacyl-CoA dehydrogenase) | UniProt NCBI |
| NOVA2 | RNA-binding protein Nova-2 (Astrocytic NOVA1-like RNA-binding protein) (Neuro-oncological ventral antigen 2) | UniProt NCBI |
| PRCP | Lysosomal Pro-X carboxypeptidase (EC 3.4.16.2) (Angiotensinase C) (Lysosomal carboxypeptidase C) (Proline carboxypeptidase) (Prolylcarboxypeptidase) (PRCP) | UniProt NCBI |
| GSTZ1 | Maleylacetoacetate isomerase (MAAI) (EC 5.2.1.2) (GSTZ1-1) (Glutathione S-transferase zeta 1) (EC 2.5.1.18) | UniProt NCBI |
| NOVA1 | RNA-binding protein Nova-1 (Neuro-oncological ventral antigen 1) (Onconeural ventral antigen 1) (Paraneoplastic Ri antigen) (Ventral neuron-specific protein 1) | UniProt NCBI |
| GLTP | Glycolipid transfer protein (GLTP) | UniProt NCBI |
| ECHS1 | Enoyl-CoA hydratase, mitochondrial (EC 4.2.1.17) (Enoyl-CoA hydratase 1) (Short-chain enoyl-CoA hydratase) (SCEH) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-77352 | 9.49682863429e-05 | 0.285714285714 | HADH ECHS1 | Beta oxidation of butanoyl-CoA to acetyl-CoA |
| REAC:R-HSA-77348 | 0.000316419251483 | 0.285714285714 | HADH ECHS1 | Beta oxidation of octanoyl-CoA to hexanoyl-CoA |
| REAC:R-HSA-77310 | 0.000316419251483 | 0.285714285714 | HADH ECHS1 | Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA |
| REAC:R-HSA-77350 | 0.000316419251483 | 0.285714285714 | HADH ECHS1 | Beta oxidation of hexanoyl-CoA to butanoyl-CoA |
| REAC:R-HSA-77346 | 0.000474522632096 | 0.285714285714 | HADH ECHS1 | Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA |
| REAC:R-HSA-77286 | 0.00113808966034 | 0.285714285714 | HADH ECHS1 | mitochondrial fatty acid beta-oxidation of saturated fatty acids |
| WP:WP357 | 0.00231614132512 | 0.285714285714 | HADH ECHS1 | Fatty Acid Biosynthesis |
| KEGG:00062 | 0.00249893990045 | 0.285714285714 | HADH ECHS1 | Fatty acid elongation |
| KEGG:00650 | 0.00249893990045 | 0.285714285714 | HADH ECHS1 | Butanoate metabolism |
| WP:WP143 | 0.00560981609224 | 0.285714285714 | HADH ECHS1 | Fatty Acid Beta Oxidation |
| KEGG:00380 | 0.00655764034054 | 0.285714285714 | HADH ECHS1 | Tryptophan metabolism |
| WP:WP465 | 0.00702347294811 | 0.285714285714 | HADH ECHS1 | Tryptophan metabolism |
| KEGG:00071 | 0.00846817863856 | 0.285714285714 | HADH ECHS1 | Fatty acid degradation |
| KEGG:00280 | 0.0106200361328 | 0.285714285714 | HADH ECHS1 | Valine, leucine and isoleucine degradation |
| KEGG:01212 | 0.0135196539521 | 0.285714285714 | HADH ECHS1 | Fatty acid metabolism |
| REAC:R-HSA-77289 | 0.0166025057177 | 0.285714285714 | HADH ECHS1 | Mitochondrial Fatty Acid Beta-Oxidation |
| KEGG:00310 | 0.01792209342 | 0.285714285714 | HADH ECHS1 | Lysine degradation |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| NOVA2 | NOVA1 | 1.0 | 0.949 | bioplex (NOVA1) bioplex_WMM youn_WMM |
| NOVA2 | HADH | 0.112 | 0.38 | fraction |
| HADH | NOVA1 | 0.109 | 0.376 | fraction |
| NOVA1 | GSTZ1 | 0.088 | 0.354 | fraction |
| ECHS1 | GSTZ1 | 0.068 | 0.35 | fraction |
| ECHS1 | HADH | 0.049 | 0.296 | bioplex_WMM youn_WMM fraction treiber_WMM |
| PRCP | GSTZ1 | 0.047 | 0.293 | fraction |
| NOVA2 | GSTZ1 | 0.045 | 0.293 | fraction |
| GSTZ1 | GLTP | 0.041 | 0.269 | fraction |
| PRCP | HADH | 0.006 | 0.005 | bioplex_WMM WMM_only |
| PRCP | ECHS1 | 0.006 | 0.004 | bioplex_WMM WMM_only |
| HADH | GSTZ1 | 0.0 | 0.009 | fraction |
| ECHS1 | NOVA2 | 0.0 | 0.008 | fraction |
| ECHS1 | NOVA1 | 0.0 | 0.001 | fraction |
Images
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Complex HuMAP2_06927 has an average edge precision of 0.256 which is ranked 5282 out of all 6965 complexes.
Related Complexes