hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06934
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ACVR2A | Activin receptor type-2A (EC 2.7.11.30) (Activin receptor type IIA) (ACTR-IIA) (ACTRIIA) | UniProt NCBI |
| MYADM | Myeloid-associated differentiation marker (Protein SB135) | UniProt NCBI |
| FMN2 | Formin-2 | UniProt NCBI |
| TGFBR2 | TGF-beta receptor type-2 (TGFR-2) (EC 2.7.11.30) (TGF-beta type II receptor) (Transforming growth factor-beta receptor type II) (TGF-beta receptor type II) (TbetaR-II) | UniProt NCBI |
| PTGER3 | Prostaglandin E2 receptor EP3 subtype (PGE receptor EP3 subtype) (PGE2 receptor EP3 subtype) (PGE2-R) (Prostanoid EP3 receptor) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04350 | 0.0127624438559 | 0.4 | ACVR2A TGFBR2 | TGF-beta signaling pathway |
| CORUM:3026 | 0.0249780992026 | 0.2 | TGFBR2 | TGF-beta receptor II-TGF-beta1 complex |
| CORUM:3041 | 0.0249780992026 | 0.2 | TGFBR2 | TGF-beta-receptor type II homodimer complex |
| CORUM:3042 | 0.0249780992026 | 0.2 | TGFBR2 | TGF-beta receptor II-TGF-beta1 complex |
| CORUM:3025 | 0.0499494897235 | 0.2 | TGFBR2 | TGF-beta receptor II-TGF-beta3 complex |
| CORUM:3027 | 0.0499494897235 | 0.2 | TGFBR2 | TGF-beta receptor II-TGF-beta receptor I-TGF-beta1 complex |
| CORUM:3031 | 0.0499494897235 | 0.2 | TGFBR2 | Microprocessor complex |
| CORUM:6234 | 0.0499494897235 | 0.2 | TGFBR2 | TGF-betaR2-TGF-beta3 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ACVR2A | TGFBR2 | 0.169 | 0.426 | bioplex (TGFBR2) bioplex_WMM |
| PTGER3 | MYADM | 0.096 | 0.357 | bioplex (PTGER3) bioplex_WMM |
| TGFBR2 | MYADM | 0.092 | 0.356 | bioplex (TGFBR2) bioplex_WMM |
| FMN2 | TGFBR2 | 0.041 | 0.271 | bioplex (TGFBR2) bioplex_WMM |
| ACVR2A | PTGER3 | 0.015 | 0.149 | bioplex (PTGER3) bioplex_WMM |
| ACVR2A | MYADM | 0.008 | 0.086 | bioplex_WMM WMM_only |
| FMN2 | ACVR2A | 0.007 | 0.0 | bioplex_WMM WMM_only |
| FMN2 | MYADM | 0.007 | 0.005 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_06934 has an average edge precision of 0.206 which is ranked 6086 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ACVR2A | HuMAP2_01201 HuMAP2_06934 |
| MYADM | HuMAP2_06934 |
| FMN2 | HuMAP2_01201 HuMAP2_06934 |
| TGFBR2 | HuMAP2_01201 HuMAP2_06934 |
| PTGER3 | HuMAP2_05885 HuMAP2_06934 |