hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06945
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PDIA4 | Protein disulfide-isomerase A4 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 70) (ER protein 70) (ERp70) (Endoplasmic reticulum resident protein 72) (ER protein 72) (ERp-72) (ERp72) | UniProt NCBI |
| XDH | Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase (XD) (EC 1.17.1.4); Xanthine oxidase (XO) (EC 1.17.3.2) (Xanthine oxidoreductase) (XOR)] | UniProt NCBI |
| PPP1R7 | Protein phosphatase 1 regulatory subunit 7 (Protein phosphatase 1 regulatory subunit 22) | UniProt NCBI |
| PPP1R2 | Protein phosphatase inhibitor 2 (IPP-2) | UniProt NCBI |
| SUOX | Sulfite oxidase, mitochondrial (EC 1.8.3.1) | UniProt NCBI |
| PPP2R5D | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PP2A B subunit isoform B'-delta) (PP2A B subunit isoform B56-delta) (PP2A B subunit isoform PR61-delta) (PP2A B subunit isoform R5-delta) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4507 | 0.000117258071898 | 0.333333333333 | XDH SUOX | Molybdenum cofactor (Moco) biosynthesis |
| CORUM:6066 | 0.0249904952816 | 0.166666666667 | XDH | Xanthine oxidase |
| GO:0019888 | 0.0422297014162 | 0.5 | PPP2R5D PPP1R7 PPP1R2 | protein phosphatase regulator activity |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PDIA4 | PPP1R7 | 0.176 | 0.435 | bioplex_WMM fraction |
| SUOX | PPP1R7 | 0.141 | 0.404 | fraction |
| PDIA4 | SUOX | 0.118 | 0.391 | bioplex (SUOX) fraction |
| PDIA4 | XDH | 0.102 | 0.366 | fraction |
| PPP2R5D | PPP1R7 | 0.045 | 0.283 | fraction |
| PPP1R7 | PPP1R2 | 0.044 | 0.279 | hein_WMM bioplex_WMM Guru boldt youn_WMM fraction boldt_WMM |
| PPP2R5D | PPP1R2 | 0.007 | 0.005 | youn_WMM gupta_WMM WMM_only |
| PDIA4 | PPP2R5D | 0.007 | 0.009 | bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| XDH | PPP2R5D | 0.0 | 0.012 | fraction |
| XDH | PPP1R2 | 0.0 | 0.006 | fraction |
| PDIA4 | PPP1R2 | 0.0 | 0.004 | bioplex_WMM youn_WMM gupta_WMM fraction |
Images
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Complex HuMAP2_06945 has an average edge precision of 0.199 which is ranked 6183 out of all 6965 complexes.
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