hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06946
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SUDS3 | Sin3 histone deacetylase corepressor complex component SDS3 (45 kDa Sin3-associated polypeptide) (Suppressor of defective silencing 3 protein homolog) | UniProt NCBI |
| SIN3B | Paired amphipathic helix protein Sin3b (Histone deacetylase complex subunit Sin3b) (Transcriptional corepressor Sin3b) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:2721 | 0.000256416289743 | 1.0 | SIN3B SUDS3 | HCF-1 complex |
| REAC:R-HSA-427413 | 0.00915054210457 | 1.0 | SIN3B SUDS3 | NoRC negatively regulates rRNA expression |
| REAC:R-HSA-5250941 | 0.0096834857656 | 1.0 | SIN3B SUDS3 | Negative epigenetic regulation of rRNA expression |
| REAC:R-HSA-212165 | 0.0177396498492 | 1.0 | SIN3B SUDS3 | Epigenetic regulation of gene expression |
| GO:0016580 | 0.0351642260875 | 1.0 | SIN3B SUDS3 | Sin3 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SUDS3 | SIN3B | 0.956 | 0.862 | hein_WMM bioplex (SUDS3) bioplex_WMM youn_WMM |
Images
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Complex HuMAP2_06946 has an average edge precision of 0.862 which is ranked 710 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SUDS3 | HuMAP2_00510 HuMAP2_03416 HuMAP2_06946 |
| SIN3B | HuMAP2_02653 HuMAP2_03329 HuMAP2_06946 |