hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_06951
Confidence: Extremely High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PYCR2 | Pyrroline-5-carboxylate reductase 2 (P5C reductase 2) (P5CR 2) (EC 1.5.1.2) | UniProt NCBI |
| PYCR1 | Pyrroline-5-carboxylate reductase 1, mitochondrial (P5C reductase 1) (P5CR 1) (EC 1.5.1.2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-8964539 | 0.000110610948517 | 1.0 | PYCR2 PYCR1 | Glutamate and glutamine metabolism |
| KEGG:00330 | 0.000164572429785 | 1.0 | PYCR2 PYCR1 | Arginine and proline metabolism |
| WP:WP4290 | 0.000320792526609 | 1.0 | PYCR2 PYCR1 | Metabolic reprogramming in colon cancer |
| KEGG:01230 | 0.000362555397177 | 1.0 | PYCR2 PYCR1 | Biosynthesis of amino acids |
| GO:0004735 | 0.00270494046827 | 1.0 | PYCR2 PYCR1 | pyrroline-5-carboxylate reductase activity |
| GO:0055129 | 0.00270494046827 | 1.0 | PYCR2 PYCR1 | L-proline biosynthetic process |
| GO:0006561 | 0.00450823411379 | 1.0 | PYCR2 PYCR1 | proline biosynthetic process |
| HP:0000325 | 0.0149105669023 | 1.0 | PYCR2 PYCR1 | Triangular face |
| GO:0006560 | 0.020287053512 | 1.0 | PYCR2 PYCR1 | proline metabolic process |
| GO:0009084 | 0.0410249304355 | 1.0 | PYCR2 PYCR1 | glutamine family amino acid biosynthetic process |
| HP:0000272 | 0.0479709504034 | 1.0 | PYCR2 PYCR1 | Malar flattening |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PYCR2 | PYCR1 | 1.0 | 0.949 | hein_WMM bioplex (PYCR1,PYCR2) bioplex_WMM boldt youn_WMM Malo gupta_WMM fraction boldt_WMM treiber_WMM |
Images
Click to enlarge
Complex HuMAP2_06951 has an average edge precision of 0.949 which is ranked 5 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PYCR2 | HuMAP2_00177 HuMAP2_00369 HuMAP2_00616 HuMAP2_03284 HuMAP2_05934 HuMAP2_06951 |
| PYCR1 | HuMAP2_00177 HuMAP2_00369 HuMAP2_00616 HuMAP2_05934 HuMAP2_06951 |