hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06959
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ENAH | Protein enabled homolog | UniProt NCBI |
| EVL | Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein-like) | UniProt NCBI |
| VASP | Vasodilator-stimulated phosphoprotein (VASP) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-202433 | 1.03407289531e-06 | 1.0 | VASP ENAH EVL | Generation of second messenger molecules |
| GO:0005522 | 1.08982291228e-05 | 1.0 | VASP ENAH EVL | profilin binding |
| KEGG:04015 | 2.55027583186e-05 | 1.0 | VASP ENAH EVL | Rap1 signaling pathway |
| REAC:R-HSA-202403 | 8.92382428809e-05 | 1.0 | VASP ENAH EVL | TCR signaling |
| REAC:R-HSA-376176 | 0.00071395360032 | 1.0 | VASP ENAH EVL | Signaling by ROBO receptors |
| GO:0017124 | 0.00251749092736 | 1.0 | VASP ENAH EVL | SH3 domain binding |
| REAC:R-HSA-422475 | 0.0100572742862 | 1.0 | VASP ENAH EVL | Axon guidance |
| REAC:R-HSA-1280218 | 0.0202947578047 | 1.0 | VASP ENAH EVL | Adaptive Immune System |
| CORUM:6731 | 0.0249904952816 | 0.333333333333 | VASP | VASP-CXCR2 complex, CXCL8 stimulated |
| GO:0008154 | 0.0406485782564 | 1.0 | VASP ENAH EVL | actin polymerization or depolymerization |
| CORUM:3160 | 0.0499776345577 | 0.333333333333 | VASP | RIAM-VASP complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ENAH | EVL | 0.998 | 0.941 | bioplex (EVL) bioplex_WMM Malo gupta_WMM fraction |
| ENAH | VASP | 0.945 | 0.856 | hein_WMM bioplex (VASP) bioplex_WMM boldt Malo gupta_WMM fraction boldt_WMM |
| VASP | EVL | 0.766 | 0.75 | bioplex (EVL,VASP) bioplex_WMM Malo fraction |
Images
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Complex HuMAP2_06959 has an average edge precision of 0.849 which is ranked 770 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ENAH | HuMAP2_00542 HuMAP2_06959 |
| EVL | HuMAP2_00542 HuMAP2_04884 HuMAP2_06959 |
| VASP | HuMAP2_00542 HuMAP2_06959 |