hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06967
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| GRAMD1B | Protein Aster-B (GRAM domain-containing protein 1B) | UniProt NCBI |
| GRAMD2B | GRAM domain-containing protein 2B (HCV NS3-transactivated protein 2) | UniProt NCBI |
| GRAMD1C | Protein Aster-C (GRAM domain-containing protein 1C) | UniProt NCBI |
| GRAMD1A | Protein Aster-A (GRAM domain-containing protein 1A) | UniProt NCBI |
| EFCAB14 | EF-hand calcium-binding domain-containing protein 14 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0140268 | 5.0832789986e-05 | 0.6 | GRAMD1B GRAMD1C GRAMD1A | endoplasmic reticulum-plasma membrane contact site |
| GO:0071397 | 5.0832789986e-05 | 0.6 | GRAMD1B GRAMD1C GRAMD1A | cellular response to cholesterol |
| GO:0036315 | 0.000149729915117 | 0.6 | GRAMD1B GRAMD1C GRAMD1A | cellular response to sterol |
| GO:0120020 | 0.000330213415772 | 0.6 | GRAMD1B GRAMD1C GRAMD1A | cholesterol transfer activity |
| GO:0070723 | 0.000330213415772 | 0.6 | GRAMD1B GRAMD1C GRAMD1A | response to cholesterol |
| GO:0120015 | 0.000412725169389 | 0.6 | GRAMD1B GRAMD1C GRAMD1A | sterol transfer activity |
| GO:0015248 | 0.000616695699567 | 0.6 | GRAMD1B GRAMD1C GRAMD1A | sterol transporter activity |
| GO:0036314 | 0.000616695699567 | 0.6 | GRAMD1B GRAMD1C GRAMD1A | response to sterol |
| GO:0044232 | 0.00160515829483 | 0.6 | GRAMD1B GRAMD1C GRAMD1A | organelle membrane contact site |
| GO:0120013 | 0.00646290954968 | 0.6 | GRAMD1B GRAMD1C GRAMD1A | lipid transfer activity |
| GO:0097306 | 0.0103850554114 | 0.6 | GRAMD1B GRAMD1C GRAMD1A | cellular response to alcohol |
| GO:0015485 | 0.0111628079368 | 0.6 | GRAMD1B GRAMD1C GRAMD1A | cholesterol binding |
| GO:0032934 | 0.0166549756635 | 0.6 | GRAMD1B GRAMD1C GRAMD1A | sterol binding |
| GO:0043178 | 0.0376065209581 | 0.6 | GRAMD1B GRAMD1C GRAMD1A | alcohol binding |
| GO:0005496 | 0.0394222084305 | 0.6 | GRAMD1B GRAMD1C GRAMD1A | steroid binding |
| GO:0097305 | 0.0472676873043 | 0.6 | GRAMD1B GRAMD1C GRAMD1A | response to alcohol |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| GRAMD2B | EFCAB14 | 1.0 | 0.949 | bioplex (GRAMD2B) bioplex_WMM |
| GRAMD2B | GRAMD1B | 0.983 | 0.899 | bioplex (GRAMD2B) bioplex_WMM youn_WMM |
| GRAMD2B | GRAMD1C | 0.904 | 0.828 | bioplex (GRAMD2B) bioplex_WMM |
| GRAMD1A | GRAMD2B | 0.584 | 0.664 | bioplex (GRAMD2B) bioplex_WMM youn_WMM |
| GRAMD1C | GRAMD1B | 0.078 | 0.352 | bioplex (GRAMD1B) bioplex_WMM |
| GRAMD1A | GRAMD1B | 0.034 | 0.262 | bioplex (GRAMD1B) bioplex_WMM youn_WMM |
| GRAMD1B | EFCAB14 | 0.009 | 0.108 | bioplex_WMM WMM_only |
| GRAMD1A | GRAMD1C | 0.009 | 0.097 | bioplex_WMM WMM_only |
| GRAMD1C | EFCAB14 | 0.009 | 0.098 | bioplex_WMM WMM_only |
| GRAMD1A | EFCAB14 | 0.008 | 0.025 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_06967 has an average edge precision of 0.428 which is ranked 3041 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| GRAMD1B | HuMAP2_01669 HuMAP2_05127 HuMAP2_06967 |
| GRAMD2B | HuMAP2_01669 HuMAP2_05127 HuMAP2_06967 |
| GRAMD1C | HuMAP2_01669 HuMAP2_05127 HuMAP2_06967 |
| GRAMD1A | HuMAP2_01546 HuMAP2_05127 HuMAP2_06967 |
| EFCAB14 | HuMAP2_01669 HuMAP2_05127 HuMAP2_06967 |