hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06968
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| LDB1 | LIM domain-binding protein 1 (LDB-1) (Carboxyl-terminal LIM domain-binding protein 2) (CLIM-2) (LIM domain-binding factor CLIM2) (hLdb1) (Nuclear LIM interactor) | UniProt NCBI |
| SSBP2 | Single-stranded DNA-binding protein 2 (Sequence-specific single-stranded-DNA-binding protein 2) | UniProt NCBI |
| SSBP4 | Single-stranded DNA-binding protein 4 | UniProt NCBI |
| ISL2 | Insulin gene enhancer protein ISL-2 (Islet-2) | UniProt NCBI |
| ISL1 | Insulin gene enhancer protein ISL-1 (Islet-1) | UniProt NCBI |
| LMO4 | LIM domain transcription factor LMO4 (Breast tumor autoantigen) (LIM domain only protein 4) (LMO-4) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:2214 | 5.0322056017e-05 | 0.333333333333 | LDB1 LMO4 | LMO4-BRCA1-CTIP-LDB1 complex |
| GO:0048934 | 0.0405595771497 | 0.333333333333 | ISL2 ISL1 | peripheral nervous system neuron differentiation |
| GO:0048935 | 0.0405595771497 | 0.333333333333 | ISL2 ISL1 | peripheral nervous system neuron development |
| CORUM:140 | 0.0499726005494 | 0.166666666667 | LDB1 | E-box sequence-binding complex |
| CORUM:3181 | 0.0499726005494 | 0.166666666667 | LMO4 | LMO4-CREB complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| LDB1 | SSBP4 | 1.0 | 0.949 | bioplex (SSBP4) bioplex_WMM |
| LMO4 | SSBP4 | 0.998 | 0.937 | bioplex (SSBP4) bioplex_WMM |
| LDB1 | SSBP2 | 0.994 | 0.923 | bioplex (SSBP2) bioplex_WMM |
| SSBP4 | ISL1 | 0.99 | 0.909 | bioplex (SSBP4) bioplex_WMM |
| SSBP4 | ISL2 | 0.987 | 0.901 | bioplex (SSBP4) bioplex_WMM |
| SSBP2 | SSBP4 | 0.984 | 0.899 | bioplex (SSBP2,SSBP4) bioplex_WMM |
| SSBP2 | ISL2 | 0.918 | 0.841 | bioplex (SSBP2) bioplex_WMM |
| SSBP2 | ISL1 | 0.789 | 0.758 | bioplex (SSBP2) bioplex_WMM |
| SSBP2 | LMO4 | 0.428 | 0.576 | bioplex (SSBP2) bioplex_WMM |
| ISL2 | ISL1 | 0.021 | 0.191 | bioplex_WMM WMM_only |
| LDB1 | ISL2 | 0.016 | 0.161 | bioplex_WMM WMM_only |
| LDB1 | LMO4 | 0.015 | 0.14 | bioplex_WMM WMM_only |
| LMO4 | ISL2 | 0.014 | 0.143 | bioplex_WMM WMM_only |
| LDB1 | ISL1 | 0.014 | 0.143 | bioplex_WMM WMM_only |
| LMO4 | ISL1 | 0.013 | 0.151 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_06968 has an average edge precision of 0.575 which is ranked 2055 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| LDB1 | HuMAP2_01442 HuMAP2_03224 HuMAP2_06968 |
| SSBP2 | HuMAP2_03224 HuMAP2_06968 |
| SSBP4 | HuMAP2_03224 HuMAP2_06968 |
| ISL2 | HuMAP2_03224 HuMAP2_06968 |
| ISL1 | HuMAP2_03224 HuMAP2_06968 |
| LMO4 | HuMAP2_03224 HuMAP2_06968 |