hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06979
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SMC1A | Structural maintenance of chromosomes protein 1A (SMC protein 1A) (SMC-1-alpha) (SMC-1A) (Sb1.8) | UniProt NCBI |
| PDS5A | Sister chromatid cohesion protein PDS5 homolog A (Cell proliferation-inducing gene 54 protein) (Sister chromatid cohesion protein 112) (SCC-112) | UniProt NCBI |
| PDS5B | Sister chromatid cohesion protein PDS5 homolog B (Androgen-induced proliferation inhibitor) (Androgen-induced prostate proliferative shutoff-associated protein AS3) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:5432 | 4.50712536095e-09 | 1.0 | PDS5A SMC1A PDS5B | Sororin-cohesin complex |
| CORUM:1856 | 4.50712536095e-09 | 1.0 | PDS5A SMC1A PDS5B | Sororin-cohesin complex |
| REAC:R-HSA-2470946 | 5.39516293207e-08 | 1.0 | PDS5A SMC1A PDS5B | Cohesin Loading onto Chromatin |
| REAC:R-HSA-2468052 | 7.41834903159e-08 | 1.0 | PDS5A SMC1A PDS5B | Establishment of Sister Chromatid Cohesion |
| REAC:R-HSA-68884 | 1.63653275606e-07 | 1.0 | PDS5A SMC1A PDS5B | Mitotic Telophase/Cytokinesis |
| GO:0007064 | 0.000120788706111 | 1.0 | PDS5A SMC1A PDS5B | mitotic sister chromatid cohesion |
| REAC:R-HSA-2500257 | 0.000126264796487 | 1.0 | PDS5A SMC1A PDS5B | Resolution of Sister Chromatid Cohesion |
| REAC:R-HSA-69242 | 0.000295546575822 | 1.0 | PDS5A SMC1A PDS5B | S Phase |
| REAC:R-HSA-2467813 | 0.000451723953992 | 1.0 | PDS5A SMC1A PDS5B | Separation of Sister Chromatids |
| REAC:R-HSA-68877 | 0.000513949964862 | 1.0 | PDS5A SMC1A PDS5B | Mitotic Prometaphase |
| REAC:R-HSA-68882 | 0.000513949964862 | 1.0 | PDS5A SMC1A PDS5B | Mitotic Anaphase |
| REAC:R-HSA-2555396 | 0.000522107900813 | 1.0 | PDS5A SMC1A PDS5B | Mitotic Metaphase and Anaphase |
| GO:0007062 | 0.0015707980909 | 1.0 | PDS5A SMC1A PDS5B | sister chromatid cohesion |
| REAC:R-HSA-68886 | 0.00398320383305 | 1.0 | PDS5A SMC1A PDS5B | M Phase |
| REAC:R-HSA-69278 | 0.0102351006549 | 1.0 | PDS5A SMC1A PDS5B | Cell Cycle, Mitotic |
| REAC:R-HSA-1640170 | 0.0176005573074 | 1.0 | PDS5A SMC1A PDS5B | Cell Cycle |
| GO:0000775 | 0.0380729634404 | 1.0 | PDS5A SMC1A PDS5B | chromosome, centromeric region |
| GO:0000070 | 0.0397775372938 | 1.0 | PDS5A SMC1A PDS5B | mitotic sister chromatid segregation |
| CORUM:5241 | 0.0499776345577 | 0.333333333333 | SMC1A | SMC1-SMC3 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PDS5B | PDS5A | 1.0 | 0.949 | hein_WMM bioplex_WMM youn_WMM Malo gupta_WMM fraction treiber_WMM |
| PDS5B | SMC1A | 0.998 | 0.937 | hein_WMM bioplex_WMM youn_WMM hein (SMC1A) Malo gupta_WMM fraction treiber_WMM |
| PDS5A | SMC1A | 0.996 | 0.928 | hein_WMM bioplex_WMM youn_WMM hein (SMC1A) Malo gupta_WMM fraction boldt_WMM treiber_WMM |
Images
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Complex HuMAP2_06979 has an average edge precision of 0.938 which is ranked 405 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SMC1A | HuMAP2_00301 HuMAP2_01398 HuMAP2_03467 HuMAP2_05244 HuMAP2_06979 |
| PDS5A | HuMAP2_00301 HuMAP2_01398 HuMAP2_05244 HuMAP2_05717 HuMAP2_06979 |
| PDS5B | HuMAP2_00301 HuMAP2_01398 HuMAP2_05244 HuMAP2_06979 |