hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06980
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SYNRG | Synergin gamma (AP1 subunit gamma-binding protein 1) (Gamma-synergin) | UniProt NCBI |
| AP1AR | AP-1 complex-associated regulatory protein (2c18) (Adaptor-related protein complex 1-associated regulatory protein) (Gamma-1-adaptin brefeldin A resistance protein) (GBAR) (Gamma-BAR) (Gamma-A1-adaptin and kinesin interactor) (Gadkin) | UniProt NCBI |
| HEATR5B | HEAT repeat-containing protein 5B | UniProt NCBI |
| AP1S2 | AP-1 complex subunit sigma-2 (Adaptor protein complex AP-1 subunit sigma-1B) (Adaptor-related protein complex 1 subunit sigma-1B) (Clathrin assembly protein complex 1 sigma-1B small chain) (Golgi adaptor HA1/AP1 adaptin sigma-1B subunit) (Sigma 1B subunit of AP-1 clathrin) (Sigma-adaptin 1B) (Sigma1B-adaptin) | UniProt NCBI |
| AFTPH | Aftiphilin | UniProt NCBI |
| AP1G2 | AP-1 complex subunit gamma-like 2 (Gamma2-adaptin) (G2ad) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:144 | 1.89127694841e-07 | 0.5 | AP1AR AP1G2 AP1S2 | Gamma-BAR-AP1 complex |
| GO:0030119 | 8.66795236882e-06 | 0.666666666667 | AP1S2 AP1G2 SYNRG AFTPH | AP-type membrane coat adaptor complex |
| GO:0030121 | 1.81582264982e-05 | 0.5 | AFTPH SYNRG AP1G2 | AP-1 adaptor complex |
| GO:0030130 | 6.35345863999e-05 | 0.5 | AFTPH SYNRG AP1G2 | clathrin coat of trans-Golgi network vesicle |
| GO:0012510 | 0.000101639975642 | 0.5 | AFTPH SYNRG AP1G2 | trans-Golgi network transport vesicle membrane |
| CORUM:36 | 0.000234668084372 | 0.333333333333 | AP1S2 AP1G2 | AP1 adaptor complex |
| GO:0030117 | 0.000395345440439 | 0.666666666667 | AP1S2 AP1G2 SYNRG AFTPH | membrane coat |
| GO:0048475 | 0.000395345440439 | 0.666666666667 | AP1S2 AP1G2 SYNRG AFTPH | coated membrane |
| GO:0030131 | 0.000518697707158 | 0.5 | AFTPH SYNRG AP1G2 | clathrin adaptor complex |
| GO:0030125 | 0.00147880241807 | 0.5 | AFTPH SYNRG AP1G2 | clathrin vesicle coat |
| GO:0030140 | 0.0032070828615 | 0.5 | AFTPH SYNRG AP1G2 | trans-Golgi network transport vesicle |
| GO:0030118 | 0.00416378298645 | 0.5 | AFTPH SYNRG AP1G2 | clathrin coat |
| REAC:R-HSA-432720 | 0.0131143608537 | 0.333333333333 | AP1S2 AP1G2 | Lysosome Vesicle Biogenesis |
| GO:0030120 | 0.0292571070793 | 0.5 | AFTPH SYNRG AP1G2 | vesicle coat |
| HPA:028020_22 | 0.0335079427243 | 0.833333333333 | AFTPH HEATR5B AP1G2 SYNRG AP1AR | lymph node; non-germinal center cells[Approved,Medium] |
| KEGG:04142 | 0.0423326508178 | 0.333333333333 | AP1S2 AP1G2 | Lysosome |
| GO:0030133 | 0.0488951273836 | 0.666666666667 | AP1AR AP1G2 SYNRG AFTPH | transport vesicle |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SYNRG | AP1S2 | 1.0 | 0.949 | hein_WMM bioplex (AP1S2) bioplex_WMM youn_WMM hein (AP1S2) |
| AFTPH | AP1S2 | 1.0 | 0.949 | hein_WMM bioplex (AP1S2) bioplex_WMM youn_WMM hein (AP1S2) |
| AP1S2 | AP1AR | 0.999 | 0.949 | hein_WMM bioplex (AP1S2) bioplex_WMM hein (AP1S2) |
| HEATR5B | AP1S2 | 0.999 | 0.948 | hein_WMM bioplex (AP1S2) bioplex_WMM hein (AP1S2) |
| AP1S2 | AP1G2 | 0.998 | 0.941 | hein_WMM bioplex (AP1S2) bioplex_WMM hein (AP1S2) |
| SYNRG | AP1G2 | 0.042 | 0.27 | hein_WMM bioplex (AP1G2) bioplex_WMM |
| AFTPH | HEATR5B | 0.013 | 0.147 | hein_WMM bioplex_WMM youn_WMM WMM_only boldt_WMM |
| SYNRG | HEATR5B | 0.012 | 0.146 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| SYNRG | AFTPH | 0.011 | 0.141 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| HEATR5B | AP1AR | 0.01 | 0.116 | hein_WMM bioplex_WMM WMM_only |
| AP1AR | AP1G2 | 0.01 | 0.098 | hein_WMM bioplex_WMM WMM_only |
| HEATR5B | AP1G2 | 0.01 | 0.103 | hein_WMM bioplex_WMM WMM_only |
| AFTPH | AP1AR | 0.01 | 0.105 | hein_WMM bioplex_WMM WMM_only |
| AFTPH | AP1G2 | 0.009 | 0.113 | hein_WMM bioplex_WMM WMM_only |
| SYNRG | AP1AR | 0.009 | 0.107 | hein_WMM bioplex_WMM WMM_only |
Images
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Complex HuMAP2_06980 has an average edge precision of 0.405 which is ranked 3262 out of all 6965 complexes.
Related Complexes