hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06983
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SYT4 | Synaptotagmin-4 (Synaptotagmin IV) (SytIV) | UniProt NCBI |
| CTSO | Cathepsin O (EC 3.4.22.42) | UniProt NCBI |
| RAPGEF6 | Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2) | UniProt NCBI |
| CD68 | Macrosialin (Gp110) (CD antigen CD68) | UniProt NCBI |
| GRN | Progranulin (PGRN) (Acrogranin) (Epithelin precursor) (Glycoprotein of 88 Kda) (GP88) (Glycoprotein 88) (Granulin precursor) (PC cell-derived growth factor) (PCDGF) (Proepithelin) (PEPI) [Cleaved into: Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Epithelin-2) (Granulin B); Granulin-4 (Epithelin-1) (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)] | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04142 | 0.0291793560441 | 0.4 | CTSO CD68 | Lysosome |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| GRN | SYT4 | 0.274 | 0.487 | bioplex (GRN) bioplex_WMM |
| CTSO | GRN | 0.045 | 0.285 | bioplex (CTSO) bioplex_WMM |
| RAPGEF6 | GRN | 0.031 | 0.237 | bioplex (GRN) bioplex_WMM |
| CD68 | GRN | 0.027 | 0.229 | bioplex (CD68) bioplex_WMM |
| RAPGEF6 | SYT4 | 0.008 | 0.082 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_06983 has an average edge precision of 0.264 which is ranked 5158 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SYT4 | HuMAP2_04986 HuMAP2_05167 HuMAP2_06983 |
| CTSO | HuMAP2_03513 HuMAP2_05167 HuMAP2_06796 HuMAP2_06983 |
| RAPGEF6 | HuMAP2_01662 HuMAP2_06983 |
| CD68 | HuMAP2_04851 HuMAP2_06983 |
| GRN | HuMAP2_04986 HuMAP2_05167 HuMAP2_06983 |