hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_06992
Confidence: Extremely High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SKIV2L | Helicase SKI2W (Ski2) (EC 3.6.4.-) (Helicase-like protein) (HLP) | UniProt NCBI |
| TTC37 | Tetratricopeptide repeat protein 37 (TPR repeat protein 37) (SKI3 homolog) (Ski3) (Tricho-hepatic-enteric syndrome protein) (Thespin) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1168 | 5.02777038712e-06 | 1.0 | TTC37 SKIV2L | SKI complex |
| HP:0009886 | 5.00914901532e-05 | 1.0 | TTC37 SKIV2L | Trichorrhexis nodosa |
| HP:0040130 | 0.000183668797228 | 1.0 | TTC37 SKIV2L | Abnormal serum iron concentration |
| REAC:R-HSA-429958 | 0.000201110815485 | 1.0 | TTC37 SKIV2L | mRNA decay by 3' to 5' exoribonuclease |
| HP:0011031 | 0.000220402556674 | 1.0 | TTC37 SKIV2L | Abnormality of iron homeostasis |
| KEGG:03018 | 0.000415808000786 | 1.0 | TTC37 SKIV2L | RNA degradation |
| HP:0011472 | 0.000454162844056 | 1.0 | TTC37 SKIV2L | Abnormality of small intestinal villus morphology |
| HP:0011473 | 0.000454162844056 | 1.0 | TTC37 SKIV2L | Villous atrophy |
| HP:0011030 | 0.000510933199563 | 1.0 | TTC37 SKIV2L | Abnormal blood transition element cation concentration |
| HP:0002224 | 0.000571042987746 | 1.0 | TTC37 SKIV2L | Woolly hair |
| HP:0003328 | 0.00117214086958 | 1.0 | TTC37 SKIV2L | Abnormal hair laboratory examination |
| GO:0055087 | 0.00135247023414 | 1.0 | TTC37 SKIV2L | Ski complex |
| HP:0002299 | 0.00234762117185 | 1.0 | TTC37 SKIV2L | Brittle hair |
| REAC:R-HSA-429914 | 0.00258092213206 | 1.0 | TTC37 SKIV2L | Deadenylation-dependent mRNA decay |
| HP:0000445 | 0.0113640893994 | 1.0 | TTC37 SKIV2L | Wide nose |
| HP:0001394 | 0.0196559007361 | 1.0 | TTC37 SKIV2L | Cirrhosis |
| HP:0001518 | 0.0284352692436 | 1.0 | TTC37 SKIV2L | Small for gestational age |
| HP:0011220 | 0.0288727349243 | 1.0 | TTC37 SKIV2L | Prominent forehead |
| HP:0010719 | 0.032028498804 | 1.0 | TTC37 SKIV2L | Abnormality of hair texture |
| HP:0002244 | 0.0491096969462 | 1.0 | TTC37 SKIV2L | Abnormality of the small intestine |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SKIV2L | TTC37 | 1.0 | 0.949 | hein_WMM bioplex_WMM youn_WMM gupta_WMM fraction |
Images
Click to enlarge
Complex HuMAP2_06992 has an average edge precision of 0.949 which is ranked 5 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SKIV2L | HuMAP2_00385 HuMAP2_05230 HuMAP2_06349 HuMAP2_06992 |
| TTC37 | HuMAP2_05230 HuMAP2_06349 HuMAP2_06992 |