hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_07005
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| MESD | LRP chaperone MESD (LDLR chaperone MESD) (Mesoderm development LRP chaperone MESD) (Mesoderm development candidate 2) (Mesoderm development protein) (Renal carcinoma antigen NY-REN-61) | UniProt NCBI |
| GALNS | N-acetylgalactosamine-6-sulfatase (EC 3.1.6.4) (Chondroitinsulfatase) (Chondroitinase) (Galactose-6-sulfate sulfatase) (GalN6S) (N-acetylgalactosamine-6-sulfate sulfatase) (GalNAc6S sulfatase) | UniProt NCBI |
| ARSA | Arylsulfatase A (ASA) (EC 3.1.6.8) (Cerebroside-sulfatase) [Cleaved into: Arylsulfatase A component B; Arylsulfatase A component C] | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04142 | 0.00307537091529 | 0.666666666667 | ARSA GALNS | Lysosome |
| REAC:R-HSA-2206290 | 0.0498572752401 | 0.333333333333 | GALNS | MPS IV - Morquio syndrome A |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ARSA | GALNS | 0.918 | 0.841 | bioplex (ARSA) bioplex_WMM |
| ARSA | MESD | 0.063 | 0.346 | bioplex (ARSA) bioplex_WMM |
| GALNS | MESD | 0.004 | 0.012 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_07005 has an average edge precision of 0.4 which is ranked 3328 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| MESD | HuMAP2_01300 HuMAP2_01923 HuMAP2_02252 HuMAP2_07005 |
| GALNS | HuMAP2_00018 HuMAP2_03210 HuMAP2_07005 |
| ARSA | HuMAP2_00018 HuMAP2_02252 HuMAP2_03210 HuMAP2_07005 |