hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_07010
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| MLXIPL | Carbohydrate-responsive element-binding protein (ChREBP) (Class D basic helix-loop-helix protein 14) (bHLHd14) (MLX interactor) (MLX-interacting protein-like) (WS basic-helix-loop-helix leucine zipper protein) (WS-bHLH) (Williams-Beuren syndrome chromosomal region 14 protein) | UniProt NCBI |
| MLX | Max-like protein X (Class D basic helix-loop-helix protein 13) (bHLHd13) (Max-like bHLHZip protein) (Protein BigMax) (Transcription factor-like protein 4) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-163765 | 3.51943927099e-05 | 1.0 | MLX MLXIPL | ChREBP activates metabolic gene expression |
| KEGG:04931 | 0.000751518249842 | 1.0 | MLX MLXIPL | Insulin resistance |
| KEGG:04932 | 0.00128068864242 | 1.0 | MLX MLXIPL | Non-alcoholic fatty liver disease (NAFLD) |
| WP:WP4396 | 0.00347096768628 | 1.0 | MLX MLXIPL | Nonalcoholic fatty liver disease |
| REAC:R-HSA-163685 | 0.00780309964082 | 1.0 | MLX MLXIPL | Integration of energy metabolism |
| HP:0001646 | 0.0175420398516 | 1.0 | MLX MLXIPL | Abnormal aortic valve morphology |
| HP:0100545 | 0.024648352588 | 1.0 | MLX MLXIPL | Arterial stenosis |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| MLXIPL | MLX | 0.998 | 0.945 | bioplex (MLX) bioplex_WMM |
Images
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Complex HuMAP2_07010 has an average edge precision of 0.945 which is ranked 362 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| MLXIPL | HuMAP2_01462 HuMAP2_06774 HuMAP2_07010 |
| MLX | HuMAP2_01462 HuMAP2_01563 HuMAP2_04173 HuMAP2_06774 HuMAP2_07010 |