hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_07018
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SMG6 | Telomerase-binding protein EST1A (EC 3.1.-.-) (EST1-like protein A) (Ever shorter telomeres 1A) (Smg-6 homolog) (Telomerase subunit EST1A) (hSmg5/7a) | UniProt NCBI |
| GNE | Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (UDP-GlcNAc-2-epimerase/ManAc kinase) [Includes: UDP-N-acetylglucosamine 2-epimerase (hydrolyzing) (EC 3.2.1.183) (UDP-GlcNAc-2-epimerase) (Uridine diphosphate-N-acetylglucosamine-2-epimerase); N-acetylmannosamine kinase (EC 2.7.1.60) (ManAc kinase)] | UniProt NCBI |
| C2orf68 | UPF0561 protein C2orf68 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-4085011 | 0.0498572752401 | 0.333333333333 | GNE | Defective GNE causes sialuria, Nonaka myopathy and inclusion body myopathy 2 |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SMG6 | C2orf68 | 0.989 | 0.905 | bioplex (C2orf68) bioplex_WMM |
| C2orf68 | GNE | 0.819 | 0.773 | bioplex (C2orf68) bioplex_WMM |
| SMG6 | GNE | 0.008 | 0.086 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_07018 has an average edge precision of 0.588 which is ranked 2001 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SMG6 | HuMAP2_00770 HuMAP2_02026 HuMAP2_07018 |
| GNE | HuMAP2_00770 HuMAP2_03540 HuMAP2_07018 |
| C2orf68 | HuMAP2_00770 HuMAP2_07018 |